adrenal cortex

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Related to adrenal cortex: adrenal medulla, aldosterone


 [kor´teks] (pl. cor´tices) (L.)
the outer layer of an organ or other structure, as distinguished from its inner substance or medulla. adj., adj cor´tical.
adrenal cortex (cortex of adrenal gland) the outer, firm layer comprising the larger part of the adrenal gland; it secretes mineralocorticoids, androgens, and glucocorticoids.
cerebellar cortex the superficial gray matter of the cerebellum.
cerebral cortex (cortex cerebra´lis) the convoluted layer of gray matter covering each cerebral hemisphere. See also brain.
renal cortex the granular outer layer of the kidney, composed mainly of glomeruli and convoluted tubules, extending in columns between the pyramids that constitute the renal medulla.
striate cortex part of the occipital lobe that receives the fibers of the optic radiation and serves as the primary receiving area for vision. Called also first visual area.
visual cortex the area of the occipital lobe of the cerebral cortex concerned with vision; the striate cortex is also called the first visual area, and the adjacent second and third visual areas serve as its association areas.

cortex of suprarenal gland

the outer part of the adrenal gland, consisting of three zones from without inward: zona glomerulosa, zona fasciculata, and zona reticularis; this part of the adrenal cortex yields steroid hormones such as corticosterone, deoxycorticosterone, and estrone.

adrenal cortex

The outer portion of the adrenal glands that produces several steroid hormones, including cortisol and aldosterone.

adrenal cortex

Etymology: L, ad, to, ren, kidney
the outer and greater portion of the adrenal gland, fused with the gland's medulla. In response to adrenocorticotropic hormone secreted by the adenohypophysis, it secretes cortisol and androgens. Adrenal androgens serve as precursors that are converted by the liver to testosterone and estrogens. Renin from the kidney controls adrenal cortical production of aldosterone. Compare adrenal medulla. adrenocortical, adj.

Adrenal Cortex

The firm, outer yellow layer of the adrenal gland which is derived from embryonic mesoderm and consists of 3 layers:
• Zona glomerulosa, the outermost layer, which secretes  mineralocorticoids, primarily aldosterone
• Zona fasciculata, the middle layer, which secretes glucocorticoids, primarily cortisol, both at baseline levels and in bursts, when so commanded by ACTH from the anterior pituitary gland
• Zona reticularis, the innermost layer, which secretes androgens, primarily dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEA-S).

adrenal cortex

The outer zone of the ADRENAL GLAND that secretes CORTISOL, sex hormones (ANDROGENS) and ALDOSTERONE. See also ADRENAL MEDULLA.

Adrenal cortex

The outer tissue of the adrenal gland. It produces a group of chemically related hormones called corticosteroids that control mineral and water balance in the body and include aldosterone and cortisol.
Mentioned in: Adrenal Gland Scan

cor·tex of su·pra·re·nal gland

(kōrteks sūpră-rēnăl gland) [TA]
The outer part of the suprarenal gland.
Synonym(s): adrenal cortex.


1. near the kidney.
2. of or produced by the adrenal glands.
3. an adrenal gland.

adrenal cortex
the outer part of the adrenal gland made up of an external zona glomerulosa, a deeper zona fasciculata and a zona reticularis. It produces three main groups of hormones, the glucocorticoids which are concerned with increasing blood glucose levels, the mineralocorticoids concerned with the maintenance of electrolyte levels in the extracellular fluid, and androgens which have the same masculinizing effect as the hormone testosterone produced by the testis. Called also adrenal gland cortex. See glucocorticoid, mineralocorticoid, androgen.
adrenal cortex inhibitors
adrenal cortical dysfunction
adrenal function tests
see acth response test, dexamethasone suppression test, v-test.
adrenal hyperplasia-like syndrome
a congenital abnormality of adrenal steroidogenesis reported in dogs which results in hyperprogestinism and hyperandrogenism. Clinical signs include bilaterally symmetrical alopecia resembling that seen with other endocrinopathies.
adrenal insufficiency
hypofunction of the adrenal gland, particularly the cortex, leading to signs of weakness and loss of sodium, chloride and water. See also primary hypoadrenocorticism.
adrenal medulla
a glandular extension of the effector fibers of the sympathetic nervous system that releases into the bloodstream the hormones epinephrine (adrenaline) and norepinephrine (noradrenaline). When the sympathetic nervous system is stimulated the adrenal medulla responds also and its hormones are carried via the bloodstream to cause increases in cardiac output and metabolic rate, vasoconstriction and reduction of gastrointestinal peristalsis. The hormones have similar functions but epinephrine is removed from the bloodstream more slowly and has a more prolonged effect. Called also adrenal gland medulla.
Adrenal medullary hormones are not essential to life. Hypersecretion, such as occurs in some functional pheochromocytomas, causes tachycardia, edema and cardiac hypertrophy.
adrenal steroids
cortisol, corticosterone, cortisone, 11-dehydroxycortisone, desoxycorticosterone, 17-hydroxy-11-desoxycorticosterone, aldosterone, the adrenal corticoids from the adrenal cortex. Called also corticosteroids.


pl. cortices [L.] an outer layer, as the bark of the trunk or root of a tree, or the outer layer of an organ or other structure, as distinguished from its inner substance.

adrenal cortex
the outer, firm layer comprising the larger part of the adrenal gland; it secretes a number of hormones. See corticosteroid, aldosterone, mineralocorticoid, glucocorticoid.
cerebellar cortex
the superficial gray matter of the cerebellum.
cerebral cortex, cortex cerebri
the convoluted layer of gray matter covering each cerebral hemisphere. See also cerebral cortex.
renal cortex
the smooth-textured outer layer of the kidney, composed mainly of renal corpuscles and convoluted tubules, extending in columns between the pyramids.
References in periodicals archive ?
Unlike glucocorticoid-producing adenomas, aldosteroneproducing cortical neoplasms are not associated with cortical atrophy, (12,13,15,19-22) and paradoxical ZG hyperplasia can be identified in the nontumorous adrenal cortex (Figure 1, D).
The normal response of the HPA axis to septic aggression consists in the release of cortisol from the adrenal cortex.
At the microscopic level, the lesions were composed of mature adipose tissue, hematopoietic cells and hyperplasia of zona reticularis of adrenal cortex.
Early history of research on adrenocortical hormones: extracts from the adrenal cortex and the physiological effect
Androgens, including testosterone, are produced by the adrenal cortex, but the amount is negligible compared with that produced by the gonads.
Corticosteroids deficiency leads to raised adrenocorticotrophic hormone (ACTH) which stimulates adrenal cortex to produce more androgenic hormones leading to features of masculinization (development of male characteristics in a genotypical female) of female fetus resulting in ambiguous genitalia.
ACTH travels via the systemic circulation to reach the adrenal cortex, wherein glucocorticoids are synthesized and released (see Herman et al.
Addison's disease, or primary adrenal insufficiency, is a chronic disorder of the adrenal cortex resulting in inadequate production of glucocorticoids and mineralocorticoids.
The other stress hormone is cortisol, a steroid hormone secreted in the adrenal cortex.
The pituitary, in turn, secretes adrenocorticotropic hormone (ACTH), which regulates the adrenal cortex, and modulates production by the ovaries, of the key sex hormones estrogen and progesterone.
This disease is characterized by the accumulation of unsaturated fatty acids with a chain of 24-30 carbons, particularly hexacosanoate in the adrenal cortex and in certain sphingolipids of the brain.