ADOPT

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ADOPT

Cardiology
Accupril Decision On PharmacoTherapy. A clinical trial that was planned at Vanderbilt University in Tennessee, the purpose of which was to compare efficacy and safety of quinapril, enalapril, atenolol and verapamil in controlling blood pressure in patients with uncomplicated mild to moderate hypertension when used as single-agent therapy in a structured titration program.
 
Endocrinology
A Diabetes Outcome Progression Trial. A 4-year Phase-4 trial comparing early treatment of type-2 diabetics with rosiglitazone (Avandia), metformin or glyburide (a sulfonylurea in glucose control) for delay or prevention of diabetes complications—e.g., kidney disease, etc.

Conclusion
Lower failure rate at 5 years: 15% with rosiglitazone vs. 21% with metformin and 34% with glyburide; a highly significant risk reduction of 32% for rosiglitazone compared with metformin, and 63% compared with glyburide. Positive results notwithstanding, rosiglitazone has been pulled from various markets due to possible increased risk of heart attacks.

ADOPT

Endocrinology A 4-yr phase IV trial–A Diabetes Outcome Progression Trial–comparing early treatment of Pts with type 2 DM with Avandia®, metformin, or glyburide–a sulfonylurea in glucose control, delay or prevention of DM complications–eg, kidney disease, etc
References in periodicals archive ?
The degree of adoptability, which respondents have given, is indicated on a scale of 1-5 as [1] a scheme is hard to adopt, [2] a scheme is slightly hard to adopt, [3] a scheme is not hard or easy to adopt, [4] a scheme is slightly easy to adopt, and [5] a scheme is easy to adopt.
In a world where the single greatest advantage a culture can have is the ability to foster adaptability and adoptability," he writes, "the Muslim world "is dominated by a religious clergy that literally bans itihad, reinterpretation of the principles of Islam in light of current circumstances.
In the past, misconceptions regarding adoptability of children with disabilities resulted in significant barriers to their successful adoption.
The feasibility and adoptability by farmers of split application needs to be tested further.
154) Likewise, the Central Authority of the sending country must supply the receiving country with a report on the adoptability of any prospective child.
Under the TUR framework, products that seem to perform well technically in terms of the EHS attributes used in the study reported here must also be as cost-effective as the traditional product to ensure easy adoptability and adaptability.
Identificational adoptability to the artistic situation becomes yet another feature of this theory and finally selective alterations and limited accessibility become the last directions in which the theory appears to have gone.
Gill's commitment to an expansive concept of adoptability reflects the admirable conviction, shared by most professionals since 1950, that all children deserve permanent kin.
The cultural relationship and contacts of Native Hawaiians with the Maori of New Zealand who provided the early impetus for FGC, the small size of the state, and its pattern of political-bureaucratic centralization allowing for statewide adoption of a uniform program, all made for statewide adoptability of this innovation.
103) holding that the juvenile court was not required to make findings of the adoptability of children as part of its determination of what is best for the children and ultimately of whether to terminate parental rights.