adjuvanticity

adjuvanticity

/ad·ju·van·tic·i·ty/ (aj″dbobr-van-tis´ĭ-te) (ă-joo″van-tis´ĭ-te) the ability to modify the immune response.
References in periodicals archive ?
Intrinsic adjuvanticity and propensity to be manipulated potentially make OMVs an ideal vaccine platform, particularly indicated when antigen combinations (for pathogens with genetic variability) and strong potentiation of immunity (for the elderly and cancer) are needed.
the length, the number, and the composition of sugar side chains affecting the HLB value would give the overall conformation of each saponin molecule, and the amphipathic structure may define the fundamental adjuvanticity of saponins (Oda et al.
The high HLB value of QS may account for its strong adjuvanticity on the basis that several saponins reported to be strong adjuvants demonstrated higher HLB values (Bomford et al.
A role of IgM antibodies in monosodium urate crystal formation and associated adjuvanticity.
Adjuvanticity and protective immunity elicited by Leishmania donovani antigen encapsulated in positively charged liposomes.
Adjuvanticity of CTB or LTB is much improved when coupled to antigens.
5a) some of which consist of polypeptide chain extensions (48), that are substantially reduced in, or in some cases practically devoid of, enterotoxic activity, but retain detectable adjuvanticity when given to animals by a mucosal route (49).
Many of these systems hold promise for future vaccine strategies, but only a few have been tested in humans for safety and adjuvanticity.
Does adjuvanticity depend on the ability to recruit specific immune cells?
However, subsequent studies indicated that the ADP-ribosyltransferase activity was not essential for the adjuvant function, and that separation of this toxic component in many instances did not hamper the adjuvanticity appreciably (52).
Mucosal adjuvanticity and immunogenicity of LTR72, a novel mutant of Escherichia coli heat-labile enterotoxin with partial knockout of ADP-ribosyltransferase activity.
Adjuvanticity and protective immunity elicited by Bordetella pertussis antigens encapsulated in poly(DL-lactide-coglycolide) microspheres.