adhesin


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Related to adhesin: IgA protease

adhesin

(ăd-hē′sĭn, -zĭn)
n.
Any of various substances present on the surfaces of bacterial cells that facilitate binding to the cells of a host and that are used as antigens in some vaccines.

adhesin

[adhē′sin]
a bacterial product that enables bacteria to adhere to and colonize a host. Adherence is often an essential step in pathogenesis. Adhesins are attractive candidates for vaccines and/or components of accellular vaccines such as those for pertussis.

Adhesin

Any of a number of bacterial virulence factors—e.g., pili in Pseudomonas aeruginosa, lipotechoic acid in group A streptococci—which jut from the surface of the bacteria and bind to glycoprotein or glycolipid receptors on host epithelial cells, facilitating bacterial adherence, a critical step in bacterial infections. Adhesins are useful targets for experimental vaccines, which reduce colonisation by uropathogenic E coli. Adhesins explains the pulmonary morbidity due to P aeruginosa seen in intubated ITU/ICU patients, and UTIs caused by E coli are mediated by MS and MR adhesins, which may be inhibited by fruit juices.

adhesin

a microbial surface component, for example FIMBRIA or PILUS, that mediates ADHESION of a microorganism to a cell or substratum. Adhesion to specific host RECEPTORS is often a preliminary stage in pathogenesis (see PATHOGEN). Adhesins are important VIRULENCE factors.
References in periodicals archive ?
pneumoniae is a genetically conserved organism, which implies limits to potential typing targets; most frequently used is P1, the main adhesin and most immunogenic protein, where sequence variation occurs mainly in the 2 copies of repetitive elements RepMP2/3 and RepMP4 of the P1-encoding locus mpn141.
Als adhesin proteins give the yeast an ability to thrive throughout the human body, which is what makes it such a dangerous infection," said Ernesto Cota, a medical biologist at Imperial College London.
dermatitidis' in Blastomyces adhesin 1 (bad1) gibi adezyon icin onemli bir reseptor ve TNF-[alpha] inhibisyonuna neden olan major bir virulans faktorunu kodlayan BAD1 null mutant bir fare modelinde attenue edilmis ve koruma saglamistir (17).
Other new produtcts in 2007 include Pattex PL600 Instant Tack, Dorus FD 150/6 LS, Adhesin FiberPlus, Bonderite 2718, Granocoat X, Hysol QMI 708, Hysol QMI 5100/5200, Loctite 435/438, Loctite Cure Jet LED, Metylan Power Granulate plus, MiraFoil, P3 Disperse, Sista Universal Seal and Repair, Sista Easy Silicone and Tangit FP Fire Protect System.
pneumoniae was accompanied by significant increases in capsule-specific IgG, as well as by small but significant increases in antibodies to both pneumolysin and pneumococcal surface adhesin A (PsaA), but not to pneumococcal surface protein A (PspA), with higher levels of anti-capsular antibodies at the outset being associated with a reduction in carriage.
epidermidis has the capability of synthesizing and secreting a polysaccharide intercellular adhesin consisting of 2 forms, polysaccharide I and II.
Furthermore, in causative strains of Escherichia coli (the causative agent in 16 of 47 of the EPN cases, and in 60%-70% of cases in general), the papG II adhesin gene was identified significantly less often than in non-EPN E.
STRUCTURAL EVALUATION OF THE N-TERMINAL REGION OF CHOLINE BINDING PROTEIN A, THE MAJOR ADHESIN OF STREPTOCOCCUS PNEUMONIAE.
Neisseria gonorrhoeaeexpresses a special adhesin protein called Opa, which allows it to invade human cells.
2t]-dependent adhesin in the attachment of Rhizobium leguminosarum to pea root hairs tips.
As the first application challenge, a new variant of a modified bacterial adhesin, Spycatcher, will be created with an altered specificity for synthetic biology applications.
HISTOLYTICA QUIK CHEK test targets an adhesin unique to E.