Therefore, in this paper, the effects of safflomide and serotomide on cAMP production were investigated in renal epithelial OK because of the link between 5-HT1 receptors and G alpha i/G alpha o proteins that regulate adenylyl
cyclase activity (Lanfumey and Hamon, 2004; Malmberg and Strange, 2000).
Using pheochromocytoma (PC12) cells, a tumor cell line that displays the major phases of neurodevelopment targeted by the pesticide, the authors evaluated the different treatments in terms of DNA synthesis, cell number (as indicated by measured amounts of DNA), cell size (as indicated by the ratio of protein to DNA), and cell signaling mediated by adenylyl
1989) results in activation of adenylyl
cyclase and, consequently, increased cAMP.
Macromolecular synthesis, adenylyl
cyclise signalling, nuclear transcription factors, and formation of reactive oxygen in C6 glioma cells.
2]-receptors that are coupled to the adenylyl
cyclase system through G proteins.
cyclase activator forskolin was purchased from Sigma-Aldrich, Inc.
Critical periods for chlorpyrifos-induced developmental neurotoxicity: alterations in adenylyl
cyclase signaling in adult rat brain regions after gestational or neonatal exposure.
Atypical regulation of hepatic adenylyl
cyclase and adrenergic receptors during a critical developmental period: agonists evoke supersensitivity accompanied by failure of receptor downregulation.
Adolescent nicotine administration alters serotonin receptors and cell signaling mediated through adenylyl
Macromolecule synthesis, adenylyl
cyclase signaling, nuclear transcription factors, and formation of reactive oxygen in C6 glioma cells.
During some stages of development, selected regions of the brain are vulnerable to CPF by interference with the G-protein in the adenylyl
cyclase (AC) cascade by disrupting nuclear transcription DNA binding (Meyer et al.
Perinatal exposure to environmental tobacco smoke alters cell signaling in a primate model: autonomic receptors and the control of adenylyl
cyclase activity in heart and lung.