adenyl cyclase


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Related to adenyl cyclase: Adenylyl cyclase

ad·e·nyl cy·clase

(ad'e-nil sī'klās),
An enzyme that converts adenosine monophosphate to 3',5'-cyclic adenosine monophosphate, an intracellular second messenger of neural and hormonal activation.

adenyl cyclase

/ad·e·nyl cy·clase/ (ad´ĕ-nil si´klās) an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic adenosine monophosphate (cAMP) and inorganic pyrophosphate (PPi). It is activated by the attachment of a hormone or neurotransmitter to a specific membrane-bound receptor.

adenyl cyclase

the enzyme that catalyses the formation of cyclic AMP (cAMP) from ATP by the removal of pyrophosphate.

ad·e·nyl cy·clase

(ad'e-nil sī'klās)
An enzyme that converts adenosine monophosphate to 3',5'-cyclic adenosine monophosphate, an intracellular second messenger of neural and hormonal activation.

adenyl cyclase

see adenylate cyclase.
References in periodicals archive ?
ADP-induced platelet activation relies on the G protein response and the eicosanoid synthesis pathway to suppress adenyl cyclase activity and induce calcium mobilization to the platelet cytosol.
The mutation leads to a loss of guanosine triphosphatase activity and thus to adenyl cyclase overactivity and subsequent overproduction of cyclic adenosine monophosphate (cAMP).
5) The cause is believed to involve a point mutation on chromosome 20 (20q12-q13) within the Gs alpha region; as a result of the mutation, the activity of the Gs protein, and thus of adenyl cyclase, is increased.
Comparing the phospho-ERK ICW to other standard assays of GPCR function, neither agonist-induced Ca2+ mobilization, as monitored by FLIPR, nor agonist-mediated inhibition of adenyl cyclase was observed yet dopamine-induced phospho-ERK was elevated five- to six-fold indicating that the phospho-ERK ICW was extremely sensitive.
In particular, tannic acid supplementation decreased both basal and isoproterenol-stimulated lipolysis significantly whereas cyclic AMP production as well as adenyl cyclase activity increased significantly.

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