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adenyl cyclase

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adenyl cyclase /ad·e·nyl cy·clase/ (ad´ĕ-nil si´klās) an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic adenosine monophosphate (cAMP) and inorganic pyrophosphate (PPi). It is activated by the attachment of a hormone or neurotransmitter to a specific membrane-bound receptor.
adenyl cyclase
see adenylate cyclase.


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The pharmacologic effects of a beta 2-adrenoceptor agonist drugs stimulate adenyl cyclase to cyclic 3'5' adenosine monophosphate (cyclic AMP).
The mutation leads to a loss of guanosine triphosphatase activity and thus to adenyl cyclase overactivity and subsequent overproduction of cyclic adenosine monophosphate (cAMP).
In particular, tannic acid supplementation decreased both basal and isoproterenol-stimulated lipolysis significantly whereas cyclic AMP production as well as adenyl cyclase activity increased significantly.
 
 
 
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