adenine phosphoribosyltransferase


Also found in: Acronyms, Wikipedia.

ad·e·nine phosphoribosyltransferase

[MIM*102600]
an enzyme that catalyzes the reaction of adenine with 5-phospho-α-d-ribose 1-diphosphate (PRPP) to form AMP and pyrophosphate. An important step in purine salvage. A deficiency of this enzyme can lead to 2,8-dihydroxyadenine lithiasis.