addressin


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ad·dres·sin

(ad-res'in),
A molecule on the surface of a cell that serves as a homing device to direct another molecule to a specific location.
[address, fr. O.Fr. adresser, to direct, fr. L.L. addirectiare, fr. L. ad, to, + directus, straight, direct, + -in]

addressin

A protein encoded by MADCAM1 on chromosome 19p13.3, which is a member of the immunoglobulin family and similar to ICAM1 and VCAM1. It is an endothelial cell-adhesion molecule which interacts preferentially with the leukocytes beta7 integrin LPAM-1, L-selectin and VLA-4 on myeloid cells, directing leukocytes into mucosal and inflamed tissues.

ad·dres·sin

(ă-dres'in)
A molecule on the surface of a cell that serves as a homing device to direct another molecule to a specific location.
[address, fr. O.Fr. adresser, to direct, fr. L.L. addirectiare, fr. L. ad, to, + directus, straight, direct, + -in]
References in periodicals archive ?
Vedolizumab, a gut-selective immunosuppressive biologic, is a humanized monoclonal antibody that is designed to specifically antagonize the alpha4beta7 integrin, inhibiting binding to intestinal mucosal addressin cell adhesion molecule 1 (MAdCAM-1) and fibronectin, but not vascular cell adhesion molecule 1 (VCAM-1).
On Friday morning police also received a report of afirearm being discharged at a second addressin Brunswick during the evening which caused damage to a window.
brBusiness name and addressIn addition to the business name and address, it is necessary to indicate the manufacturer or packager, if independent to the main business and the seller.
Injured " Mourinho was 16 minutes late to the press conference - a period in which Guardiola was addressin the issue to the media ahead of City's trip to Swansea.
SHP647 is a fully human IgG2 monoclonal antibody that targets the mucosal addressin cell adhesion molecule-1 (MAdCAM-1).
The same email called on Katie -- who also has Bunny, three, Jett,four, Princess, 10, and Junior, 12 -- to deliver the cash to an addressin London.
In mesenteric lymph node HEVs, MAdCAM-1, a sialomucin bearing two immunoglobulin-like domains, (15) serves as a vascular addressin, and [alpha]4[beta]7 integrin serves as the cognate lymphocyte receptor that mediates rolling and adhesion, (16) as described below.
Minister Bathiudeen was addressin the launch event of the unique FMCG promotion campaign "Idam Nidhaanaya" (Land Treasure) by Lanka SATHOSA and Unilever Lanka where consumers get access to a pioneering sweepstake to win one of three prime land plots developed and ready for them.
Ringler, "Monoclonal antibodies specific for [beta]7 integrin and mucosal addressin cell adhesion molecule-1 (MAdCAM-1) reduce inflammation in the colon of scid mice reconstituted with CD45RBhigh [CD4.
from=singlemessage&isappinstalled=0#/play/1840 Frank Underwood AaAaAeAeAaAeAeA inAaAaAeAeAaAeAeA the Netflix series "House of Cards," andAaAaAeAeAaAeAeA addressin shoppers from the "Oval Office,"AaAaAeAeAaAeAeA also attracted the attention of Internet users -- not least for its possibly ironic reference to Underwood being unable to shopAaAaAeAeAaAeAeA online himself, due to what he said wereAaAaAeAeAaAeAeA f affectingAaAaAeAeAaAeAeA the White House's computer netw
Focused or planning and enacting I in classroom, assisting students, and addressin administrative issues with PBL implementation.
Organisation Mission : For GEF SGP, the community-based approach is the cornerstone for addressin