Carnitine, acetylcarnitine and the activity of carnitine acyltransferases
in seminal plasma and spermatozoa of men, rams and rats.
The authors observed no systematic differences in TRI-mediated induction of hepatic PPAR[alpha] target genes; however, TRI significantly increased expression of triglyceride (TG)-synthesizing enzymes, diacylglicerol acyltransferases
, and PPAR[gamma] in Ppar[alpha]-null and hPPAR[alpha] mice, which may account for the increased TG in their livers.
The first section, on improvement of agronomic and microbial traits, contains 11 papers on areas such as molecular strategies for enhancing seed oil content, engineering biosynthesis of alpha-eleostearic acid in transgenic systems, cloning and characterization of Kennedy pathway acyltransferases
from developing seeds of tung, and accumulation of epoxy fatty acids in plant oils.
More specifically, Spalmitoylation is a reversible lipid modification, in which the protein undergoes cycles of palmitoylation and depalmitoylation, catalyzed by palmitoyl acyltransferases
(PATs) and palmitoyl-protein thioesterases (PPTs).
However, TRI significantly increased expression of triglyceride (TG)-synthesizing enzymes, diacyl-glicerol acyltransferases, and PPAR[gamma] in Ppar[alpha]-null and hPPAR[alpha] mice, which may account for the increased TG in their livers.
Specifically, very long chain acylcoenzyme A (CoA) dehydrogenase (VLCAD), medium chain acyl-CoA dehydrogenase (MCAD), peroxisomal bifunctional protein (hydratase + 3-hydroxyacyl-CoA dehydrogenase) (PH), peroxisomal thiolase (PT), diacylglicerol acyltransferase 1 (DGAT1), and p52 mRNA levels were higher in hPPAR[alpha] mice than in mPPAR[alpha] and Ppar[alpha]-null mice.
Clofibrate induces carnitine acyltransferases
in periportal and perivenous zones of rat liver and does not disturb the acinar zonation of gluconeoganesis.
Glycerol-3-P acyltransferase and 1-acylglycerol-3-P acyltransferase are both required for milk triglyceride synthesis (Moore and Christie, 1979).
Topology of acyltransferase motifs and substrate specificity and accessibility in 1-acyl-sn-glycero-3-phosphate acyltransferase 1.