acylate

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acylate

(as′ĭ-lāt″) [ acyl]
To incorporate an acyl (alkanoyl) group into a chemical compound.
acylation (as″ĭ-lā′shŏn)
References in periodicals archive ?
Furthermore, the aromatic amide (+)-tembamide (5), and the phenylpropanoid (+)-ailanthoidiol (6) were esterified with different acylating reagents to afford seven alkanoyi/aroyl esters (7-13).
Like simple alcohol, the hydroxyl groups of cellulose can be esterified by reactions with acids or other acylating agents.
The most commonly used initiators for cationic polymerization are protic acids, Lewis acids, stable organic salts and alkylating or acylating covalent compounds.
Derouane [6,7] studied adsorption, reaction, and deactivation of zeolite H-BEA in the acetylation of anisole with acetic acid as the acylating agent.
Ceftaroline possess improved anti-MRSA activity as a result of the altered 3' side chain that interacts with an allosteric binding site on PBP2a, allowing the [beta]-lactam ring to have optimal access to the active-site serine, acylating the site and initiating the series of biochemical events that result in bacterial cell death (120).
By acylating PF resin, Miller and Rosthauser (2002) found that the esterification of phenolic oxygen greatly reduced the reactivity of the PF portion in the resin mix when combining the pMDI to form a singlephase liquid material with a storage life of more than 2 weeks at room temperature.
However, the attractiveness of this pathway is unfortunately offset by the high cost of acylating agent.
The court held that since "one cannot chose from the unknown" and "one having no knowledge of this acid could hardly find it obvious to make any cephem using this acid as an acylating agent, much less the particular cephem," the process was nonobvious.
This new technology may have to await additional work, as the safety and toxicology of chemically reactive agents themselves (several alkylating agents, diazonium compounds and acylating agents are known to have carcinogenic, mutagenic, skin sensitizing and allergenic properties), and the FDA status of chemically modified drug active ingredients (such as sunscreen active ingredients) after such ingredients have been attached to human skin.
To compensate for possible differences in the reactivity of the acylating agent with primary and secondary amines, differing detector responses toward the amide derivatives formed with each analyte, and the expected differences in biofluid concentrations of MDMA and MDA, we deemed it appropriate to select two internal standards.
Reactions of aromatic N-oxides with enamines of cyclohexanone in the presence of acylating agents.
When comparing the results obtained in EPG85-257 cells for compounds 1-4, it can be suggested that the presence of acylating groups at C-3 and C-16 is important for the cytotoxic activity of lathyrane diterpenes in multidrug-resistant EPG85-257RDB cells, since the presence of free hydroxyl groups at these positions decreased the activity.