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acyl CoA |
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acyl CoA /ac·yl CoA/ (a´sil ko-a´) acyl coenzyme A.
acyl 1. an organic radical derived from a fatty acid by removal of the hydroxyl group. 2. generic term for fatty acid groups. acyl carrier protein ACP; a carrier protein molecule which is part of the fatty acid synthesizing enzyme complex in non-mammalian systems and which carries acyl groups. acyl CoA thioester of coenzyme A and a fatty acid of unspecified, but usually more than 14 carbon length. acyl CoA dehydrogenase deficiency lack of the first enzyme of beta-oxidation, acyl CoA dehydrogenase, a flavoprotein which catalyzes the removal of two hydrogens from the acyl chain. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| ? Mentioned in | ? References in periodicals archive | |
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Transcription regulation of peroxisomal fatty acyl CoA oxidase
and enoy-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase in rat liver by
peroxisome proliferators. Whatever the precise mechanism by which PPs induce rodent liver
cancer, rodent liver peroxisome proliferation, induction of the
peroxisomal gene acyl CoA oxidase (ACO) (23), hypertrophy (24), and
carcinogenicity (25) are all mediated through activation of the
peroxisome proliferator-activated receptor (PPAR[alpha]). cite the finding of an inactive PP response
element upstream of the acyl CoA oxidase gene in a sample human
population (15) as additional evidence for why humans may be less
responsive than rodents to PPs. |
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