acute-phase serum


Also found in: Acronyms.

acute-phase serum

Serum from a patient with a current (acute) infection for which bacterial- or viral-specific immunoglobulins (usually IgM) are measured.
Mentioned in ?
References in periodicals archive ?
Although acute-phase serum from the patients reported here was almost always collected at the time of admission and those who had symptoms >7 days before admission were excluded from enrollment, for some, a rapid, anamnestic response could have developed before admission.
Despite obtaining acute-phase serum at admission, the time of bacteremia onset could not be determined, complicating interpretation of immune response results.
All acute-phase serum samples were initially screened for IgM against WNV (WNV IgM Capture DxSelect; Focus Diagnostics Inc.
A total of 23/38 patients positive for IgM against WNV provided convalescent-phase serum samples (obtained 18-83 days after acute-phase serum samples were obtained).
Correlations between acute-phase serum antibodies against H1 and H3 and convalescent-phase serum antibodies against H7 were assessed by using the Spearman rank correlation coefficient test.
Acute-phase serum samples, clinical information, and laboratory data for all patients given a diagnosis of SFTS in 2011 in Yiyuan County were submitted to the Yiyuan County Centers for Disease Control and Prevention.
DNA was extracted from acute-phase serum and the eschar swab by using the same procedure as had been used for the first patient.
Paired serum samples are infrequently obtained, but testing acute-phase serum alone is insensitive (IgG is initially absent) and nonspecific (IgG can persist for years, and IgM results represent cross-reactions).
Virus isolation was attempted on the acute-phase serum sample by using Vero and C6/36 cells, but the culture did not yield any virus.
where paired serum samples were tested by ELISA and acute-phase serum samples were cultured and tested by PCR.
Quantitative PCR result on DNA extracted from the acute-phase serum was negative (2).
Acute leptospirosis was defined as definitive sero-conversion (negative acute-phase serum specimen to positive convalescent-phase serum specimen) or the equivalent of a 4-fold rise in IgM titer.