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acute tubular necrosis |
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acute tubular necrosis (ATN), acute renal failure with mild to severe damage or necrosis of tubule cells, usually resulting from nephrotoxicity, ischemia after major surgery, trauma (crush syndrome ), severe hypovolemia, sepsis, or burns. See also renal failure. acute tubular necrosis Nephrology A pathologic change of acute renal failure due to shock, crush injuries, hemoglobinuria, toxic nephrosis, sepsis, drugs-aminoglycosides, amphotericin B, cyclosporine, radiocontrast, ischemia in transplanted
kidneys Predisposing conditions DM, liver disease; ATN in transplanted kidneys is managed in an expectant fashion as renal function may resume spontaneously in 2-4 wks How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| ? Mentioned in | ? References in periodicals archive | |
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His acute renal failure (Table 1) was treated
with hemodialysis; it was attributed to acute tubular necrosis from
dehydration and intravascular hemolysis, superimposed on chronic renal
insufficiency from hypertensive nephrosclerosis. Prophylactic or therapeutic dosing
with FG-4539 improved renal function as evidenced by lower BUN and serum
creatinine levels, improved GFR, and prevented acute tubular necrosis as
confirmed by histological analysis. Complications during her hospitalization unrelated to babesiosis
included nosocomial pneumonia, acute tubular necrosis from
hypoperfusion, bilateral deep venous thromboses, pulmonary embolism, and
thrombocytopenia temporally associated with the initiation of heparin
therapy (Table). |
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