acute self-limited colitis

acute self-limited colitis

Transient colonic inflammation with features that overlap idiopathic bowel disease, which presents with bloody diarrhoea and resolves usually within 2–4 weeks without residual inflammation or recurrent symptoms. It is a diagnosis of exclusion—i.e., the absence of histologic criteria for diagnosing IBD. ASLC is presumed to have an infectious aetiology—in 50% of cases a specific pathogen is identified; bacterial pathogens include: Campylobacter, Shigella, Salmonella species E coli O157:H7, as well as viruses and parasites (e.g., Giardia).

DiffDx
Diversion colitis, preparations for scoping—e.g., Fleet’s enema, herbal cleansers.

Histologic criteria, acute self-limited colitis
Acute inflammation generally confined to the lamina propria
• Patchy or diffuse;
• Crypt abscesses may be present;
• Neutrophils in the crypt epithelium.

No chronic changes
• Minimal to no crypt distortion or dropout;
• No to only mild chronic inflammation of the lamina propria;
• Severe cases may be ulcerated, haemorrhagic and have microthrombi.

acute self-limited colitis

GI disease A condition with features that overlap idiopathic IBD; ASLC is a diagnosis of exclusion–absence of histologic criteria for diagnosing IBD–eg distorted crypt architecture, ↑ round cells and PMNs in lamina propria, villous surface, epithelioid granuloma(s), basal lymphoid aggregates, basal giant cells DiffDx Diversion colitis, preps for scoping–eg, Fleet's enema, herbal cleansers. See Inflammatory bowel disease.
References in periodicals archive ?
Acute infectious-type colitis or acute self-limited colitis (ASLC) may be caused by a variety of infectious agents.
The histopathologic spectrum of acute self-limited colitis (acute infectious-type colitis).
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