AFM case-patients were defined as children <21 years of age who had acute neurologic illness characterized by focal weakness of [greater than or equal to] 1 limbs, magnetic resonance imaging (MRI) findings of spinal cord lesions largely restricted to gray matter, and no identified etiology, per CDC case definition (6,7,9,10).
Acute neurologic illness of unknown etiology in children--Colorado, August-September 2014.
Outbreaks of an unexplained acute neurologic illness
affecting young children and associated with high case-fatality rates have been reported in the Muzaffarpur district of Bihar state in India since 1995.
The Centers for Disease Control and Prevention issued the alert in late September in response to an ongoing investigation in Colorado involving a cluster of nine children who have been hospitalized with acute neurologic illness
Acute neurologic illness
with focal limb weakness of unknown etiology in children.
On September 12, 2014, CDC was notified by the Colorado Department of Public Health and Environment of a cluster of nine children evaluated at Children's Hospital Colorado with acute neurologic illness
characterized by extremity weakness, cranial nerve dysfunction (e.