acute gouty arthritis


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Related to acute gouty arthritis: colchicine, chronic gout

Acute Gouty Arthritis

An abrupt gouty attack, which may be precipitated by overeating, alcohol, surgery, emotional stress, infection, antibiotics, insulin.
Clinical findings Crushing pain of a joint—typically of the big toe—which is swollen, hot, shiny.
Management, acute NSAIDs, COX-2 inhibitors, colchicine (side effects include diarrhoea and vomiting, even before pain relief), steroids and ACTH.
Management, chronic Lose weight if BMI > 28; reduce alcohol consumption, allopurinol, periodically check urate levels.

acute gouty arthritis

Acute gout Rheumatology An abrupt gouty attack, which may be precipitated by overeating, alcohol, surgery, emotional stress, infection, antibiotics, insulin Clinical Crushing pain of a joint–most often the great toe–which is swollen, hot, shiny. See Gout, Gouty arthritis.
References in periodicals archive ?
Canakinumab reduces the risk of acute gouty arthritis flares during initiation of allopurinol treatment: results of a double-blind, randomised study.
In this analysis, ARCOXIA 120 mg once daily provided effective relief for patients with moderate pain and for those with severe pain, and was comparable to indomethacin, the standard therapy for acute gouty arthritis for more than 30 years.
The analysis combined the results of two identically designed, published studies(1) that demonstrated comparable efficacy of ARCOXIA and indomethacin in acute gouty arthritis.
This randomized, double-blind study evaluated the efficacy and safety of ARCOXIA 120 mg once daily (n=103) compared with the non-selective non-steroidal anti-inflammatory drug (NSAID) indomethacin 50 mg three times daily (n=86) in the treatment of acute gouty arthritis over a seven-day treatment period.
1) Results showed that ARCOXIA 120 mg once daily provided a comparable degree of pain relief as indomethacin 50 mg three times daily in patients with acute gouty arthritis and was generally well tolerated in the study.
The company will be seeking indications for ankylosing spondylitis (a chronic, inflammatory disorder primarily involving the spine), osteoarthritis, rheumatoid arthritis, chronic pain, acute pain, dysmenorrhea (menstrual pain) and acute gouty arthritis.
Results from a study of ARCOXIA in acute gouty arthritis - the largest ever reported in patients with the disease - were published in the June 22 issue of the British Medical Journal.
Its efficacy has been proven in conditions ranging from osteoarthritis and chronic low back pain through to acute pain suffered following dental surgery and acute gouty arthritis, which is widely recognised as one of the most painful (and difficult to treat) inflammatory conditions.
Merck also is seeking indications for osteoarthritis, rheumatoid arthritis, chronic pain, acute pain, dysmenorrhea (menstrual pain) and acute gouty arthritis.

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