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Acute CholangitisAcute bile duct inflammation
Aetiology Stricture or obstruction of bile ducts, infection, pancreatic reflux, drugs, chemicals
Clinical findings Right upper quadrant pain of varying severity which may radiate to the shoulder, nausea, vomiting, constipation, episodic chills, fever, slow pulse, Murphy sign, anorexia, weight loss; spontaneous remission is rare.
Lab Increased leukocytes—especially neutrophils—increased bilirubin, urobilinogen in urine.