acute cholangitis


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Acute Cholangitis

Acute bile duct inflammation
Aetiology Stricture or obstruction of bile ducts, infection, pancreatic reflux, drugs, chemicals
Clinical findings Right upper quadrant pain of varying severity which may radiate to the shoulder, nausea, vomiting, constipation, episodic chills, fever, slow pulse, Murphy sign, anorexia, weight loss; spontaneous remission is rare.
Lab Increased leukocytes—especially neutrophils—increased bilirubin, urobilinogen in urine.
Management Cholecystectomy

acute cholangitis

Gastroenterology Acute bile duct inflammation Etiology Stricture or obstruction of bile ducts, infection, pancreatic reflux, drugs, chemicals Clinical Right upper quadrant pain that may radiate to the shoulder, variable severity, N&V, constipation, episodic chills, fever, slow pulse, Murphy sign, anorexia, weight loss; spontaneous remission is rare Imaging ERCP, percutaneous transhepatic cholangiography Lab ↑ WBCs, ↑ BR, urobilinogen in urine Management Cholecystectomy
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References in periodicals archive ?
While elevated CA 19-9 levels occur in most patients with carcinoma of the pancreas, it can also be elevated in patients with extrapancreatic malignancies and acute cholangitis.
2) However, a elevated CA 19-9 level does not necessarily indicate pancreatic cancer, as elevated levels may also be caused by benign conditions such as cirrhosis and acute cholangitis.
Conditions that are known to cause significant elevations of this assay are acute cholangitis and cirrhosis.

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