ADNF

(redirected from activity-dependent neurotrophic factor)

ADNF

Activity-dependent neurotrophic factor. A glia-derived protein that is neuroprotective at femtomolar concentrations, the main activity of which is conferred by a 9-amino acid peptide derived from ADNF and an 8-amino acid NAP.
References in periodicals archive ?
These patents cover a family of peptides comprising an entirely new class of compounds distinct from Allon's two existing neuroprotective technology platforms, activity-dependent neuroprotective protein (ADNP) and activity-dependent neurotrophic factor (ADNF).
In addition, peptide fragments derived from neurotrophic factors like glial-derived activity-dependent neuroprotective protein (ADNP) and activity-dependent neurotrophic factor (ADNF) also can reduce alcohol's teratogenic effects, in part by antagonizing alcohol's inhibition of L1 cell adhesion (Wilkemeyer et al.
Peptidergic agonists of activity-dependent neurotrophic factor protect against prenatal alcohol induced neural tube defects and serotonin neuron loss.
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