actins


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actins

Filamentary contractile proteins forming the cytoskeleton of cells. Actins contribute to cell shape, cell motility and to some internal cell functions.
References in periodicals archive ?
Protective effects of high-molecular weight Polyethylene Glycol (PEG) in human lung endothelial cell barrier regulation: role of actin cytoskeletal rearrangement," Microvascular Research, vol.
Actin is the major cytoskeletal protein and involved in a variety of processes including cellular motility, intracellular transport, cytoskeletal structure, cell-surface mobility, cytokinesis, cytoplasmic streaming, clot retardation, microvillar movement, exocytosis and endocytosis, and probably chromosomal condensation and mitosis (Sheterline et al.
Higher eukaryotic organisms express several actin genes however their primary structure is similar.
The present report describes the isolation of actin gene (partial sequence) from T.
The plasmid pTZ57R/T (Fermentas) containing ampicillin resistance gene and was used for cloning of actin gene.
Using DNA as a template, a partial actin gene was amplified by PCR technique with Taq polymerase (Fermentas).
2+], gelsolin severs and caps polymeric actin filaments (F-actin) (21): after binding of domain G1 and partly domain G2 to the actin filament (F-actin), gelsolin rapidly severs F-actin and then remains bound to the barbed end of one of the newly formed filaments, forming a stable cap, thus inhibiting addition of further monomers.
The concentration of gelsolin seems to be rate limiting in the actin removal system and depends on the rates of formation, dissociation, and clearance of the actin-gelsolin complex.
In addition to scavenging of actin, Gc-globulin also plays additional roles in some non-actin-scavenging functions (Fig.
Other tasks of Gc-globulin, such as actin binding, alter neither its binding capacity nor its affinity for vitamin D steroids.
All of these findings strongly suggest that Gc-globulin exerts more complex physiologic functions than clearance of actin released by necrotic cells and tissues from the circulation.