actinomycin


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

actinomycin

 [ak″tĭ-no-mi´sin]
a family of antibiotics from various species of Streptomyces, which are active against bacteria and fungi; it includes the antineoplastic agentdactinomycin (actinomycin D).

actinomycin

/ac·ti·no·my·cin/ (-mi´sin) a family of antibiotics from various species of Streptomyces, which are active against bacteria and fungi; it includes the antineoplastic agent dactinomycin (actinomycin D).

actinomycin

(ăk-tĭn′ō-mī′sĭn, ăk′tə-nō-)
n.
Any of a class of peptide-containing, often toxic antibiotics that are obtained from soil bacteria.

actinomycin

antibiotic agents isolated from Actinomyces species (Streptomyces ) active against Gram-positive bacteria and fungi

actinomycin

a family of antibiotics from various species of Streptomyces, which are active against bacteria and fungi; it includes the antineoplastic agents actinomycin C (cactinomycin) and actinomycin D (dactinomycin).
References in periodicals archive ?
Actinomycin (dactinomycin) 500 mcg road,albendazole 200mg tablet,albendazole 200mg / 5ml suspension bottle 10ml,phenobarbital sodium 100mg tablet,phenobarbital sodium 100mg / ml ampoule 1-2ml etc.
According to International Ewing's Sarcoma Study (IESS)-1 and IESS-2, the chemotherapy regimen consisting of vincristine (V), doxorubicin (A), cyclophosphamide (C), actinomycin (A) (VDCA protocol) was recommended.
Antimycin (40[micro]M) and actinomycin D (50[micro]M) were used as positive controls for plasma membrane integrity and cell volume, respectively.
Inhibition of transcription with actinomycin D blocked ZnO-induced IL-8 expression, which was consistent with the observation that ZnO exposure increased IL-8 promoter reporter activity.
Two- or 3-drug regimens are used, which include vincristine, actinomycin D and doxorubicin.
5] per ml L929 cell (Central Research Institute, Kasauli) suspension containing actinomycin D (A9415 Sigma Aldrich, New Delhi) was added to each well and incubated for 18 h at 37[degrees]C under 5 per cent C[O.
A THERMODYNAMIC AND KINETIC STUDY OF ACTINOMYCIN D BINDING TO ATYPICAL-T(G)nT-SEQUENCES IN DOUBLE STRANDED DNA.
Cells treated with Actinomycin D (a known inducer of apoptosis) or Sol B demonstrated the typical apoptotic DNA ladder on agarose gel electrophoresis.
7) The chemotherapeutic element of the IRS IV protocol is significantly different from its predecessors in that the newer agents etoposide, ifosfamide, and melphalan have been added to the standard treatment with vincristine, actinomycin D, and cyclophosphamide.
Borden et al (1) reported one case of a patient with hematogenous spread to the cervical spine who experienced long-term survival after successful treatment with actinomycin D, cyclophosphamide, and methotrexate.
Three weeks following surgery, she started a combination of radiotherapy and a total of 9 cycles of high-dose alkylating chemotherapy: vincristine, cyclophosphamide, actinomycin D, ifosfamide, carboplatin and etopside.
The stimulatory effect of garlic lectin on IFN-[gamma] production was completely inhibited by both actinomycin D and cycloheximide, an inhibitor of ribosomal protein synthesis and DNA-dependent RNA polymerase, respectively, and was associated with an increase in IFN-[gamma] mRNA level.