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actinomycin

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actinomycin /ac·ti·no·my·cin/ (-mi´sin) a family of antibiotics from various species of Streptomyces, which are active against bacteria and fungi; it includes the antineoplastic agent dactinomycin (actinomycin D).
ac·ti·no·my·cin (kt-n-msn)
n.
Any of a large group of red, often toxic, polypeptide antibiotics isolated from soil bacteria of several species of Streptomyces (originally Actinomyces) that are active against gram-positive bacteria and fungi.

actinomycin
a family of antibiotics from various species of Streptomyces, which are active against bacteria and fungi; it includes the antineoplastic agents actinomycin C (cactinomycin) and actinomycin D (dactinomycin).


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(7) The chemotherapeutic element of the IRS IV protocol is significantly different from its predecessors in that the newer agents etoposide, ifosfamide, and melphalan have been added to the standard treatment with vincristine, actinomycin D, and cyclophosphamide.
[25] According to Tefft et al,[26] the use of drugs such as actinomycin D, Adriamycin, and cyclophosphamide to enhance the effects of radiation has resulted in damaged bone.
Thus even with prior exposure of the cells to the toxic chemotherapeutic drug actinomycin D, the cells did not die.
 
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