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acrodermatitis enteropathica

   Also found in: Acronyms, Encyclopedia, Wikipedia 0.01 sec.
acrodermatitis /ac·ro·der·ma·ti·tis/ (-der″mah-ti´tis) inflammation of the skin of the hands or feet.
acrodermatitis chro´nica atro´phicans  chronic inflammation of the skin, usually of limbs, leading to sclerosis and atrophy of the skin, caused by the spirochete Borrelia burgdorferi.
acrodermatitis conti´nua  a variant of pustular psoriasis, with chronic inflammation of limbs that in some cases becomes generalized.
acrodermatitis enteropa´thica  a hereditary disorder due to defective zinc uptake, with a vesiculopustulous dermatitis preferentially located around orifices and on the head, elbows, knees, hands, and feet, associated with gastrointestinal disturbances, chiefly manifested by diarrhea, and total alopecia.
Hallopeau's acrodermatitis  a. continua.
infantile acrodermatitis , papular acrodermatitis of childhood Gianotti-Crosti syndrome.
acrodermatitis per´stans  a. continua.

acrodermatitis en·ter·o·path·i·ca (nt-r-pth-k)
n.
A genetic defect in the malabsorption of zinc, beginning as a skin eruption on an extremity or around a body orifice, followed by hair loss and diarrhea or other gastrointestinal disturbances.

acrodermatitis enteropathica
[en′tərōpath′ikə]
a rare, chronic disease of infants characterized by vesicles and bullae of the skin and mucous membranes, alopecia, diarrhea, and failure to thrive. An autosomal-recessive disorder of zinc malabsorption, the disease may be lethal if not treated. Zinc sulfate is usually prescribed.

acrodermatitis [ak″ro-der″mah-ti´tis]
inflammation of the skin of the limbs, especially the hands or feet.
chronic atropic acrodermatitis (acrodermatitis chro´nica atro´phicans)
1. chronic inflammation of the skin of the extremities, leading to atrophy.
2. a diffuse chronic skin disease usually confined to the limbs, seen mainly in women in Northern, Central, and Eastern Europe, and characterized initially by an erythematous, edematous, pruritic phase followed by sclerosis and atrophy. It is caused by infection with Borrelia burgdorferi. See also lyme disease.
acrodermatitis conti´nua (continuous acrodermatitis) chronic inflammation of the skin of the limbs, in some cases becoming generalized.
enteropathic acrodermatitis (acrodermatitis enteropa´thica) a hereditary disorder of infancy due to defective zinc uptake, characterized by dermatitis with vesicles and pustules, usually around the mouth or anus and on the head, elbows, knees, hands, and feet; there are also gastrointestinal disturbances such as diarrhea, as well as total alopecia.
acrodermatitis per´stans acrodermatitis continua.

acrodermatitis enteropathica
Congenital zinc deficiency An AR condition characterized by dermatitis and diarrhea; the dermatitis affects the cheeks, elbows, knees, periorbital and perianal regions, and is accompanied by hair loss on the scalp, eyebrows and lashes; AE is associated with short stature, anemia, skin hyperpigmentation, hepatosplenomegaly, hypogonadism, poor wound healing, immune deficiency, recurrent bacterial and fungal infections due to immune defect Lab ↓ serum zinc due to impaired uptake Management Oral zinc


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The syndrome of edema and hypoproteinemia, due to pancreatic enzyme deficiency may be the presenting manifestation in up to 8% of patients with CE Associated findings include hepatomegaly, elevated liver enzymes, and acrodermatitis enteropathica, and anemia.
 
 
 
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