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Acid Hemolysis Test |
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Ham Test A test that assesses susceptibility of erythrocytes to hemolysis, which is markedly increased in paroxysmal nocturnal hemoglobinuria (PNH); see there.
Principle In acidified serum, complement is activated by the alternate pathway, binds to RBCs, and lyses PNH cells which are sensitive to complement activation; positive Ham test also occurs in the rare congenital dyserythropoietic anemia type II, also known as HEMPAS acid hemolysis test Ham test Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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