aciclovir


Also found in: Dictionary, Thesaurus, Wikipedia.
Related to aciclovir: Zovirax

aciclovir

A drug highly active against the herpes simplex virus which causes cold sores and genital herpes and against the closely similar varicella-zoster virus which causes CHICKENPOX and SHINGLES. Early treatment with the drug, taken by mouth, can greatly reduce the severity of shingles. Brand names are Zovirax and Soothelip,

acyclovir, aciclovir

a synthetic analog of guanosine which selectively interferes with viral DNA synthesis. Used parenterally and topically as an antiviral agent in herpesvirus infections in cats, birds and horse.
References in periodicals archive ?
To assess whether standard and/or high doses of aciclovir and valaciclovir affect these subclinical periods of HSV reactivation, they enrolled participants into the three studies, each with a 4- to 7-week initial treatment period, followed by a 1-week washout period, followed by crossover to the other treatment for an additional 4-7 weeks.
Now at least we find that aciclovir, a very cheap, non-toxic and widely-available drug, can prolong the time some patients may be able to stay off the more expensive, and sometimes toxic, HIV drugs.
The list of drugs tested and the maximum concentrations used were as follows: mycophenolic acid (50 mg/L), famotidine (200 mg/L), trimetoprim/sulfamethoxazole (800 mg/L trimetoprim and 4 g/L sulfamethoxazole), antithrombin III (2500 IU/ L), aciclovir (250 mg/L), cyclosporine A (50 mg/L) N-acetylcysteine (500 mg/L), and tacrolimus (140 [micro]g/L).
Xerclear[R] in Europe) Xerese[TM] consists of a combination of the antiviral aciclovir with the corticosteroid hydrocortisone in a proprietary formulation.
There was also a 10% increase in the prescription of athlete's foot powder, aciclovir - the activate ingredient in cold-sore treatment Zovirax.
In a double-blind, placebo-controlled study 60 RRMS patients received aciclovir (800 mg/day) acting against herpes viruses, or placebo over 2 years.
Acyclovir and cyclosporin become aciclovir and cictosporin respectively.
The judge, Mr Justice Lloyd Jones, was told the hospital's managers have now admitted Gethin should have been treated with anti-viral drug Aciclovir - a standard treatment for the condition.
The patient described in this case received co-trimoxazole, aciclovir, itraconazole and azithromycin as prophylaxis against opportunistic infections for the duration of chemotherapy; he also did not develop an opportunistic infection.
The risk may be reduced by taking oral antiviral agents such as aciclovir within 72 hours of development of the rash.
Use an over-the-counter cream with antiviral drug aciclovir at the first sign of a tingle.
46,48,49) Management is guided by bacterial culture, staining results, and laboratory tests: systemic penicillin or a cephalosporin is used for gonorrhoeal infection; systemic erythromycin for chlamydial infection; and systemic aciclovir for herpes (virus) infection.