acetylserotonin

acetylserotonin

An acetylated form of serotonin produced in the pineal gland.

acetylserotonin

A product formed as an intermediate in the synthesis pathway for MELATONIN from SEROTONIN.
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The enzymes aryl-alkyl-N-acetyltransferase (AANAT) and acetylserotonin O-methyltransferase (ASMT), also known as hydroxyl-indole-O-methyltransferase (HIOMT), are highly conserved being detected in unicellular organisms, plants, and animals [19-21].
A simple, specific, radio-enzymatic assay for picogram quantities of serotonin or acetylserotonin in biological fluids and tissues.
Although melatonin receptors, MT1 and MT2, are present in the human retina, the presence of acetylserotonin methyltransferase (ASMT) is very low, so the receptors can bind circulating melatonin [53, 54].