acetylcholine receptors


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acetylcholine receptors

proteins which act to bind ACETYLCHOLINE at the cell surface. See CHOLINERGIC.

acetylcholine

the acetic acid ester of choline, normally present in many parts of the body and having important physiological functions. It is a neurotransmitter at cholinergic synapses in the central, sympathetic and parasympathetic nervous systems. It is not used clinically but it is the classical cholinergic agonist. Abbreviated ACh.

acetylcholine receptors
structures located at the endorgans, e.g. at the skeletal muscle fibers. The myofibers are stimulated to contract by the interaction of acetylcholine with acetylcholine receptors which are located on the motor end plate or postsynaptic sarcolemma. See also neuromuscular junction.
References in periodicals archive ?
Structure and function of insect nicotinic acetylcholine receptors studied with nicotinoid insecticide affinity probes, pp.
Acetylcholine receptor antibody characteristics in myasthenia gravis.
Cigarette smoking saturates brain alpha 4 beta 2 nicotinic acetylcholine receptors.
revealed that the "Ketek effect" may be caused by the inhibition of specific nicotinic acetylcholine receptors found in the neuromuscular junction, retina and parasympathetic innervation of the liver.
The depolarizing agents bind to acetylcholine receptors and cause a sustained postsynaptic membrane depolarization.
As they identified more and more receptor subtypes, scientists began to wonder how the brain would respond to a nicotine-like molecule that could activate just one type of acetylcholine receptor.
Alzheimer's brains show another distinct characteristic: a significant loss of cholinergic neurons and acetylcholine receptors, in addition to the hallmark plaques and tangles, said Dr.
Brains of patients with Alzheimer's disease (AD) show another distinct characteristic: a significant loss of cholinergic neurons and acetylcholine receptors, in addition to the hallmark plaques and tangles, said Dr.
One hundred or so of these toxins have been studied to date and have demonstrated such selectivity for specific receptors that some have been used, for example, to help characterize subtypes of nicotinic acetylcholine receptors in mammalian heart muscle, leading to a better understanding of the mechanisms that control heart rate and contractility (Bibevski et al.
Chapters on glutamate receptors, acetylcholine receptors, other opioid receptors, adenosine, P2 receptors, substance P/N[K.
EnVivo has demonstrated that EVP-6124 is a potent and highly selective agonist of alpha-7 neuronal nicotinic acetylcholine receptors (nAChRs) in the brain and that treatment with EVP-6124, both alone and in combination with donepezil, restored memory loss and improved memory function in preclinical models.

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