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acetylator |
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acetylator /acet·y·la·tor/ (ah-set´ĭ-la″ter) an organism capable of metabolic acetylation; in humans, acetylator status (fast or slow) is determined by the rate of acetylation of sulfamethazine. acetylator an organism capable of metabolic acetylation. Those animals that differ in their inherited ability to metabolize certain drugs, e.g. isoniazid, are termed fast or slow acetylators. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| ? Mentioned in | ? References in periodicals archive | |
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| Acetylator genotype-dependent N-acetylation of arylamines in vivo
and in vitro by hepatic and extrahepatic organ cytosols of Syrian
hamsters congenic at the polymorphic acetyltransferase locus. They obtained patient
blood samples for acetylator genotyping (NAT-2 genotype) and began to
encounter dose-limiting toxicities (primarily hematologic) at 500 mg/m2. Caffeine acetylator phenotyping during maturation in
infants. |
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