acetylation


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Related to acetylation: methylation, acetic anhydride, acylation

a·cet·y·la·tion

(a-set'i-lā'shŭn),
Formation of an acetyl derivative.

acetylation

/acet·y·la·tion/ (ah-set″ĭ-la´shun) introduction of an acetyl radical into an organic molecule.

a·cet·y·la·tion

(a-set'i-lā'shŭn)
Formation of an acetyl derivative.

acetylation (·sē·t·lā·shn),

n a phase II detoxification pathway occurring in the liver in which acetyl-CoA combines with metabolic products.

acetylation

one of the synthetic biotransformations which operate in the metabolism of drugs in which metabolites are produced that are more readily excreted than the parent drug. Dogs are exceptional amongst the domesticated species in that acetylation does not occur in their tissues. Acetylation is one of the principal metabolic pathways of the sulfonamides.
References in periodicals archive ?
All the physicochemical indices (Table 1) investigated such as true density, bulk and tapped densities, water absorption capacity, moisture content, total and acid insoluble ash, pH and amylose content reduced after acetylation of acha starch.
Offspring born to high-LG-ABN mothers had lower methylation at certain CpG sites in the promoter and increased histone acetylation, and showed higher transcription-factor binding and increased gene expression.
These results clearly demonstrated that the Keggin structure is retained after completion of the acetylation reaction.
In our modified approach, acetylation labeling mass spectrometry (ALMS), a slightly higher anhydride-to-protein ratio is used than previously reported.
As SQLs are a lipophilic agent, the acetylation may add to the lipophilicity, and hence, possibly enhances cellular penetration, and consequently augments the anti-inflammatory activity (Choi et al.
Acetylation with acetic anhydride is the only active chemical modification which has been scaled to a commercial process (Rowell 2006).
For example, serine phosphorylation regulates lysine acetylation of p53 during DNA damage (6).
The mechanism underlying the aspirin-ibuprofen interaction may be due to "competitive inhibition of the acetylation site of cyclooxygenase in the platelet," according to the FDA statement.
Alkalization and acetylation were chosen because of their wide use in the field of cellulose chemistry [10].
There are two groups of genetic factors that have been associated with the development of drug-induced SLE-HLA alleles and acetylation status in drug metabolism.
In order to investigate the role of histone acetylation in establishing an infection by simian virus 40 (SV40), we have analyzed formalin fixed and unfixed SV40 chromosomes obtained 30 minutes and 3 hours post-infection for the presence of tetraacetylated histone H4 and di-acetylated histone H3 using a combination of chromatin immunoprecipitation (ChIP) techniques including quantitative ChIP assays with competitive PCR, depletion analyses, and competitive ChIP analysis.