acetylase


Also found in: Encyclopedia.

a·cet·y·lase

(a-sĕt'il-ās),
Any enzyme catalyzing acetylation or deacetylation, as in the formation of N-acetylglutamate from glutamate plus acetyl-CoA, or the reverse; acetylases are usually called acetyltransferases.

a·cet·y·lase

(a-set'il-ās)
Any enzyme catalyzing acetylation or deacetylation, as in the formation of N-acetylglutamate from glutamate plus acetyl-CoA, or the reverse; acetylases are usually called acetyltransferases.
References in periodicals archive ?
WSG has been shown to inhibit ibotenic acid-induced cognitive deficits in rats by reversing rat brain frontal cortical and hippocampal decreases in acetylcholine, choline acetylase and cholinergic muscarinic receptors produced by the neurotoxin (Bhattacharya et al.
Exendin-4 increases histone acetylase activity and reverses epigenetic modifications that silence Pdx1 in the intrauterine growth retarded rat," Diabetologia, October 2011 print issue.
The role dietary of bioactive compounds on the regulation of histone acetylases and deacetylases: a review.
MCM3AP is an acetyltransferase that acetylases MCM3, and plays a role in DNA replication (Takei et al.
This acetylation is catalyzed by histone acetylases (HATs) that uses acetyl-CoA as substrate and the acetyl group is transferred to the [euro] amino group of certain lysine side chains within histones N-terminal tails and other nuclear receptor proteins thereby regulating chromatin remodeling and gene expression (171).
The smallest unit of chromatin is the nucleosome acetylases switch genes on by freeing DNA from tightly packed chromatin.
A set of enzymes, such as histone acetylases, histone deacetylases (HDACs), [4] histone methyltransferases, and histone demethylases, regulates these reversible processes (5, 6, 9).
These modifications are brought about by different enzymes that recruit different substrates like kinases use ATP for phosporylation; acetylases use acetyl CoA for acetylation, etc.
These processes are regulated by enzyme families called histone acetylases (HATs) and histone deacetylases (HDACs).
Study suggests that histone deacetylase enzymes cooperating with CBP/p300 histone acetylases trigger expression of many genes that respond to hypoxia, according to St.