ACSS2

(redirected from acetyl-Coenzyme A synthetase 2)

ACSS2

A gene on chromosome 20q11.22, which encodes a cytosolic enzyme that produces acetyl-CoA from acetate, for use in lipid synthesis and energy generation. ACSS2 expression is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids.
References in periodicals archive ?
In addition, the expression of acetyl-Coenzyme A synthetase 2 (categorized as a "Fatty acid oxidation" gene) was three-fold higher in mammary than liver tissue, consistent with its function of activating acetate for use in ruminant lipid synthesis and fuel support (Smith and Prior, 1986).