acetyl-CoA ligase

a·ce·tyl-CoA li·gase

(as'ĕ-til lī'gās)
A ligase that catalyzes the reaction of acetate and CoA and ATP to form AMP, pyrophosphate, and acetyl-CoA. A key step in the activation of acetate.
Synonym(s): acetate thiokinase, acetate-CoA ligase, acetyl-activating enzyme, acetyl-CoA synthetase.