acetohexamide

acetohexamide /ac·e·to·hex·a·mide/ (as″ĕ-to-hek´sah-mīd) an oral hypoglycemic used in the treatment of type 2 diabetes mellitus.

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acetoHEXAMIDE

[-hek′səmīd]

a sulfonylurea oral antidiabetic.

indication It may be prescribed in the treatment of type 2 diabetes mellitus.

contraindications Its use is prohibited as sole therapy in type 1 diabetes mellitus, diabetic ketoacidosis, severe liver or kidney dysfunction, or known hypersensitivity to this drug or to other sulfonylureas.

adverse effects Among the most serious adverse reactions are blood dyscrasias, hypoglycemia, and allergic reactions. GI disturbances are common.

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sulfonylurea [sul″fo-nil-u´re-ah]

any of a class of compounds that exert hypoglycemic activity by stimulating the islet tissue to secrete insulin; used to control hyperglycemia in patients with type 2 diabetes mellitus who cannot be treated solely by diet and exercise. The class includes the oral hypoglycemic agentsacetohexamide, chlorpropamide, glipizide, tolazamide, and tolbutamide.

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acetohexamide,

n brand names: Dimelor, Dymelor;
drug class: sulfonylurea; antidiabetic;
action: causes functioning β cells in the pancreas to release insulin, leading to a drop in blood glucose level;
uses: stable type 2 diabetes mellitus.

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acetohexamide

a first generation sulfonylurea derivative, used as an oral hypoglycemic agent in the treatment of diabetes mellitus.