acetaldehyde


Also found in: Dictionary, Thesaurus, Acronyms, Encyclopedia, Wikipedia.

acetaldehyde

 [as″et-al´de-hīd]
a colorless volatile liquid used in the manufacture of acetic acid, perfumes, and flavors, which is irritating to mucous membranes and has a general narcotic action. It is also an intermediate in the metabolism of alcohol.

ac·et·al·de·hyde

(as-e-tal'dĕ-hīd),
An intermediate in yeast fermentation of carbohydrate and in alcohol metabolism. It is a central agent for the toxic effects of ethanol.
Synonym(s): acetic aldehyde, ethanal

acetaldehyde

/ac·et·al·de·hyde/ (as″et-al´dĕ-hīd″) a colorless, volatile, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors; it is also an intermediate in the metabolism of alcohol. It can cause irritation of mucous membranes, pneumonia, headache, and unconsciousness.

acetaldehyde

(ăs′ĭ-tăl′də-hīd′)
n.
A colorless, flammable liquid, C2H4O, used to manufacture acetic acid, perfumes, and drugs.

acetaldehyde (CH3CHO)

[as′ətəldē′hīd]
a colorless, volatile liquid aldehyde with a pungent odor produced by the oxidation of ethyl alcohol. Its systematic (International Union of Pure and Applied Chemistry) name is ethanal. In the human body, acetaldehyde is produced in the liver by the action of alcohol dehydrogenase and other enzymes. It is used commercially in the manufacture of acetic acid and various aromas and flavors. Exposure to high levels of acetaldehyde can result in headache, corneal injury, rhinitis, and respiratory disorders

acetaldehyde

The major metabolic product of ethanol, which is generated by ethanol dehydrogenase and subsequently metabolised to acetate by aldehyde dehydrogenase. It is responsible for alcohol’s toxic effects.

It is postulated that the liver injury induced by ethanol is due to tissue responses to acetaldehyde, including acetaldehyde-induced fibrogenesis, acetaldehyde-induced lipid peroxidation enzyme inhibition, and formation of antibodies against acetaldehyde adduct proteins—e.g., serum albumin, hemoglobin, and cytokskeletal proteins, including tubulin.

Ref range
< 0.02 mg/dL.
 
Method
Gas chromatography.

acetaldehyde

Toxicology The major metabolic product of ethanol, which is generated by ethanol dehydrogenase and subsequently metabolized to acetate by aldehyde dehydrogenase, and responsible for drinking-alcohol's toxic effects

ac·et·al·de·hyde

(as'ĕ-tal'dĕ-hīd)
An intermediary product in the metabolism of alcohol.

acetaldehyde

A product of the metabolism of large amounts of alcohol. The reaction is catalyzed in the liver by the enzyme alcohol dehydrogenase. The principal cause of the toxic effects of strong drink. Acetaldehyde is a powerful poison, considerably more toxic than alcohol, and is capable of damaging almost any part of the body. Fortunately the body has a range of detoxifying enzymes, aldehyde dehydrogenases, one of which, ALDH2, rapidly break down the acetaldehyde molecule.

acetaldehyde

a colorless volatile liquid, CH3CHO, found in freshly distilled spirits, which is irritating to mucous membranes and has a general narcotic action. It is also an intermediate in the metabolism of alcohol.
References in periodicals archive ?
The study said that over 540 million people in Asia carry a mutation in the ALDH2 gene, which means they can't process acetaldehyde which causes the widely documented red flush reaction in Asians.
1990, 1991; Kenney, 1982, 1984), and the second is the indirect action of ethanol oxidation, which produces inhibition of the endogenous production of acetaldehyde.
At the completion of MLF, acetaldehyde and pyruvic acid concentrations were measured in these wines as well as a control wine that did not undergo MLF.
CYP2E1 reduces molecular oxygen to water and thus ethanol is oxidized to acetaldehyde.
We attempted to clarify in this experiment whether or not ethanol alone is a trigger of acetaldehyde emission.
Research studies have confirmed that acetaldehyde is the main cause of alcohol addiction.
Thirteen yeast strains were isolated capable of growing in YPD medium supplemented with 400 L benzaldehyde, one milliliter acetaldehyde and 10 mg/L of ampicillin.
Increased salivary acetaldehyde levels in heavy drinkers and smokers: a microbiological approach to oral cavity cancer.
Such processes are substituting the use of acetaldehydes, and so are restraints for the acetaldehyde market.
Five parameters were extracted from freshly cut sample data involving peaks related to esters, acetaldehyde and ethanol.
7,8] Disulfiram reacts with the ingested alcohol (disulfiram-ethanol reaction or DER) to promote acetaldehyde accumulation, which is responsible for the unpleasant reaction in alcoholics, thus making them intolerant to alcohol.
Wood panels in building materials, furniture, or vehicles include adhesives and binders, which release aldehydes such as formaldehyde and acetaldehyde during aging and heating.