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A fast-acting vitamin K-antagonist anticoagulant. In patients with proximal vein thrombosis, it can be co-administered with full-dose heparin.


A fast-acting vitamin K-antagonist anticoagulant

acenocoumarol, acenocoumarin

a warfarin derivative used as an anticoagulant. Called also nicoumalone.
References in periodicals archive ?
Rivaroxaban was discontinued, and the patient was switched to a new anticoagulant, acenocoumarol.
Differences between case-patients and controls were shown in use of statins, clopidogrel, acenocoumarol, and proton pump inhibitors and hospitalization and adequate treatment during acute Q fever (p<0.
Although the current treatment for stroke - vitamin K antagonists, acenocoumarol and phenprocoumon - can be effective, they are also associated with a number of drawbacks and are currently underused, particularly in elderly patients who are at greatest risk of stroke.
VKORC1 and CYP2C9 genotypes and acenocoumarol anticoagulation status: interaction between both genotypes affects overanticoagulation.
This was demonstrated in a cohort of 112 Dutch patients treated with acenocoumarol who received an NSAID (diclofenac, naproxen, or ibuprofen).
2,3) We studied the outcomes in patients treated with acenocoumarol for more than 6 months in a series of consecutive outpatients with VTD from a rural Spanish area.
5-5 mg twice a day, and triflusal 600 mg plus acenocoumarol to reach an INR target of 1.
His fever subsided, and he was discharged a few days later while continuing to receive acenocoumarol, an oral coumarin anticoagulant.
Cytochrome P450 2C9 (CYP2C9) and vitamin K epoxide reductase (VKORC1) genotypes as determinants of acenocoumarol sensitivity.
Drug interactions as a cause of overanticoagulation on phenprocoumon or acenocoumarol predominantly concern antibacterial drugs.
6% * Prohibited or rescue medications include: Acenocoumarol, Alteplase, Dextran, Dextran 40, Dipyridamole, Etamsilate, Heparin, Heparin Group, Heparin Sodium, Heparin Fraction (Calcium Salt or Sodium Salt), Nadroparin, Nadroparin Calcium, Phenindione, Streptokinase, Warfarin, or Warfarin Sodium on the day prior to surgery and the day of surgery (at any time prior to surgery for Etamsilate and for two days prior to surgery for Warfarin or Warfarin Sodium), or for at least three consecutive days after the first dose of study drug.