ACE

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angiotensin

 (ACE) [an″je-o-ten´sin]
a vasoconstrictive substance formed in the blood when renin is released from the juxtaglomerular apparatus in the kidney. The enzymatic action of renin acts on angiotensinogen to form the decapeptide angiotensin I, which is relatively inactive. It in turn is acted upon by peptidases (converting enzymes), chiefly in the lungs, to form the octapeptide angiotensin II, a powerful vasopressor and a stimulator of aldosterone secretion by the adrenal cortex. By its vasopressor action, it raises blood pressure and diminishes fluid loss in the kidney by restricting blood flow. Angiotensin II is hydrolyzed in various tissues to form heptapeptide angiotensin III, which has less vasopressor activity but more effect on the adrenal cortex.
angiotensin-converting enzyme (ACE) an enzyme of the hydrolase class that catalyzes cleavage of a dipeptide from the C-terminal end of angiotensin I to form activated angiotensin II; called also peptidyl-dipeptidase A.
angiotensin-converting enzyme inhibitors competitive inhibitors of angiotensin-converting enzyme, which converts angiotensin I to angiotensin II and inactivates bradykinin. ACE inhibitors, such as captopril, are antagonists of the renin-angiotensin-aldosterone system and potentiators of the kinin system and are used for treatment of hypertension, usually in conjunction with a diuretic. They are also used as vasodilators in the treatment of congestive heart failure.

ACE

ACE

ACE

(1) Abciximab & Carbostent Evaluation in Acute Myocardial Infarction. A trial comparing outcomes of carbon-coated stenting of an infarct-related artery with and without abciximab.
Primary endpoint 30-day MACE (major acute coronary events)
Conclusion Abciximab + IRA stenting may be a viable reperfusion strategy in patients with acute myocardial infarction undergoing primary percutaneous revascularization.
(2) ASA & Carotid Endarterectomy. A trial comparing high- and low-dose aspirin to reduce the risk of stroke in patients undergoing carotid endarterectomy.
Primary endpoints 30-day MACE (major acute coronary events), stroke
Conclusion Low-dose (80, 325 mg) ASA patients did better

ACE

Angiotensin-converting enzyme, see there. Cf ACE inhibitors, also
1. Acute Care for Elderly.
2. Adriamycin, cyclophosphamide, etoposide.
3. Alcohol, chloroform, ether–obsolete anesthetic cocktail.
4. American College of Epidemiology.

ACE

Abbreviation for angiotensin-converting enzyme.

ACE

See ANGIOTENSIN-CONVERTING ENZYME.

ACE

angiotensin converting enzyme

ACE,

ACE

angiotensin-converting enzyme.

ACE inhibitors
a group of drugs used as vasodilators in the management of heart failure. They act to decrease circulating levels of angiotensin II and aldosterone. See captopril, enalapril, lisinopril.

ace

acepromazine.
References in periodicals archive ?
Thirty students from the BTEC National Diploma in Performing Arts at Huddersfield Technical College are in the final stages of rehearsing the musical melodrama - The Ace of Clubs.
The ace of diamonds was taken, a spade ruffed in dummy and the ace of clubs was followed by a club ruff.
In these different ways, artistic ideas gradually spread and eventually led to Georges de la Tour painting his picture, The Cheat with the Ace of Clubs.
ACE OF CLUBS Defoe and Spurs team-mate Kyle Walker yesterday TAKING IT ON THE CHIN Jermain Defoe has had to deal head-on with tragedy
She was a lifelong member of the Immaculate Conception Church, and a former member of the Ace of Clubs.
The pounds 500 weekly prize goes to Mr J Dibben, of Lymm, who scored 56 points with his team Ace of Clubs.
Among the perfidious politicians and big business bounders featured is Sedgefield's own Mr Tony (the Ace of Clubs, no less) while Bank of England Governor Eddie George makes it in there too, thanks to his quote that job losses in the North are a "price worth paying".
The cards,dubbed the ``deck of death'', are thought to show the toppled Iraqi dictator as the Ace of Spades and his son Qusay as the Ace of Clubs.
These days, he's the ace of clubs deadly serious about transforming Bo'ness United into a junior league super power.
Whitey's fellow aces are Ace of Clubs Michael Alfonso, 34, an Illinois man who the FBI say is a violent serial killer; Ace of Hearts Glen Stewart Godwin, 49, a murderer; and Ace of Diamonds Hopeton Eric Brown, 30, wanted by Interpol for drug-related killings.
Four clubs from South shows the ace of clubs, Four diamonds by North the ace of diamonds and four hearts by South the ace of hearts.
He formed the Ace of Clubs club in Rhyl, but gave up racing at the age of 68 after he suffered a serious accident in which he lost part of his hand.