accessory cell


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an·ti·gen-·pre·sent·ing cells (APC),

cells that process protein antigens into peptides and present them on their surface in a form that can be recognized by lymphocytes. APCs include Langerhans cells, dendritic cells, macrophages, B cells, and, in humans, activated T cells.
Synonym(s): accessory cell

accessory cell

A macrophage that aids in immune recognition by binding circulating antigens, processing them and presenting them on cell surfaces so that the immune recognition cascade can proceed, which in addition secrete a broad palette of cytokines and biological response modifiers.

Binding of an antigen to a self-cell is essential for T-cell response to an antigen, as the T-cell receptor requires a self-MHC class-II molecule with a bound foreign antigen before it can respond to an antigen.

an·ti·gen-pre·sent·ing cells

(APC) (an'ti-jen-prĕ-zent'ing selz)
Cells that process protein antigens into peptides and present them on their surface in a form that can be recognized by lymphocytes. APCs include Langerhans cells, dendritic cells, macrophages, B cells, and in humans, activated T cells.
Synonym(s): accessory cell.

accessory cell

A monocyte or macrophage that participates in the immune response.
See: antigen-presenting cell; macrophage
See also: cell
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A concentrate of these cells contains "not only stem cells and precursor cells as a source of regeneration tissue, but also accessory cells that support angiogenesis and vasculogenesis by producing several growth factors and cytokines.
Cui will describe a new procedure to produce neural progenitors from hESCs which utilizes defined growth factors and requires neither multicellular aggregate formation nor accessory cells.
Because clinical improvement with Targretin is most pronounced in the skin, Targretin may also affect cytokine expression by keratinocytes and accessory cells in the local milieu of the skin.