accelerated fractionation

accelerated fractionation

The delivery of radiation at a rate of accumulation that is up to 50% faster than that of standard fractionation, which substantially decreased duration of therapy and decreased potential for tumour repopulation between fractions.

accelerated fractionation

Radiation oncology The delivery of radiation at a rate of accumulation that is up to 50% faster than that of standard fractionation, which substancially ↓ duration of therapy, and ↓ potential for tumor repopulation between fractions. See Fractionation. Cf Hyperfractionation.
References in periodicals archive ?
The long-term toxicity of high-dose radiation is often underappreciated, but it is clear that chronic fibrosis, edema, tissue necrosis, and dysphagia are not uncommon and that their incidence increases with more aggressive accelerated fractionation schemes and with long-term (>5 yr) follow-up.
Accelerated fractionation is a means of decreasing the overall duration of treatment in an effort to reduce the repopulation of tumor cells in rapidly proliferating cancers.
A variant of accelerated fractionation is the concomitant-boost technique.
This hybrid regimen incorporates features of both accelerated fractionation and hyperfractionation.
9,10] The Radiation Therapy Oncology Group recently reported the findings of its prospective, randomized, 2-year comparison of once-daily fractionation, hyperfractionation, and two variants of accelerated fractionation.
Fu KK, Pajak TF, Trotti A, et al, A Radiation Therapy Oncology Group (RTOG) phase III randomized study to compare hyperfractionation and two variants of accelerated fractionation to standard fractionation radiotherapy for head and neck squamous cell carcinomas: First report of RTOG 9003.

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