acanthosis


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Related to acanthosis: parakeratosis

acanthosis

 [ak″an-tho´sis]
diffuse hypertrophy or thickening of the prickle cell layer of the skin. adj., adj acanthot´ic.
acanthosis ni´gricans diffuse acanthosis with gray, brown, or black pigmentation, chiefly in the axillae and other body folds, occurring in an adult form, often associated with an internal carcinoma (called malignant acanthosis nigricans) and in a benign, nevoid form, more or less generalized. A benign form associated with obesity, which is sometimes due to endocrine disturbance, is called pseudo-acanthosis nigricans. (See Atlas 2, Part E).

ac·an·tho·sis

(ak-an-thō'sis),
An increase in the thickness of the stratum spinosum of the epidermis.
[G. fr. acantho-, thorn + G. -osis, condition]

acanthosis

/ac·an·tho·sis/ (ak″an-tho´sis) diffuse hyperplasia and thickening of the stratum spinosum of the epidermis.acantholyt´ic
acanthosis ni´gricans  diffuse velvety acanthosis with dark pigmentation, chiefly in the axillae; it occurs in an adult form, often associated with an internal carcinoma (malignant a. nigricans), and in a benign, nevoid form, more or less generalized. A benign juvenile form associated with obesity, which is sometimes due to endocrine disturbance, is called pseudoacanthosis nigricans.

acanthosis

[ak′ənthō′sis]
Etymology: Gk, akantha + osis, condition
an abnormal, diffuse hypertrophy of the stratum spinosum, as in eczema and psoriasis. See also acanthosis nigricans. acanthotic, adj.

acanthosis

Hyperplasia of the squamous epithelium of mucocutaneous surfaces.
Diseases with
Psoriasis, granulomatous reactions, lymphocytic infiltrates.

Mechanism
Defective epidermal cell kinetics.

ac·an·tho·sis

(ak-an-thō'sis)
An increase in the thickness of the stratum spinosum of the epidermis.
[G. fr. acantho-, thorn + G. -osis, condition]

acanthosis

A disease process in the skin featuring overgrowth and thickening of the prickle-cell layer of the EPIDERMIS. This layer lies above its parent layer, the BASAL cell layer, and local overgrowth results in raised, roughened areas such as warts or the lesions of PSORIASIS or ECZEMA.

acanthosis

increase in epidermal stratum spinosum thickness, characteristic of verrucae

ac·an·tho·sis

(ak-an-thō'sis)
Increased thickness of epidermal stratum spinosum.
[G. fr. acantho-, thorn + G. -osis, condition]

acanthosis (ak´ənthō´sis),

n an increase in the number of cells in the prickle cell layer of stratified squamous epithelium, with thickening of the entire epithelial cell layer and a broadening and fusing of rete pegs.

acanthosis

an increased thickness of the stratum spinosum, due to either an increased number or hypertrophy of cells.

frictional acanthosis
see acanthosis nigricans (below).
acanthosis nigricans
a skin disease of dogs characterized by hyperpigmentation, lichenification, seborrhea, and alopecia commencing in the axillae and often spreading to involve flexural surfaces of all limbs, and the ventral body. Dachshunds are particularly predisposed to primary acanthosis, often developing the first changes at a young age. Sporadic cases are secondary to systemic disease, endocrinopathies, hypersensitivity reactions and friction in body folds.
References in periodicals archive ?
Haematoxylin and Eosin stained Section of Lichen amyloidosis at 40x Magnification showing Hyperkeratosis, Papillomatosis, Acanthosis and Dermal Infiltrate along with Amyloid
Glycogenic acanthosis was diagnosed on histopathological examination of the specimen or the presence of typical endoscopic view (one or more, round/oval, whitish elevated lesions of the esophagus covered with normal mucosa and frequently <5 mm in diameter).
Ficca, "Is Acanthosis Nigricans a reliable indicator for risk of type 2 diabetes?
Bilateral axillary hyperpigmentation with thickening spreading to ventral abdomen, neck, groin, perineum from axial region was suggestive of Acanthosis nigricans of diverse etiology (Muller et al.
The bandlike infiltrate obscuring the dermoepidermal junction with cytoid body formation, confluent hyperkeratosis, irregular acanthosis, basal cell liquefactive degeneration, and apoptosis may closely mimic lichen planus.
In the vigorous exercise group, 24% had acanthosis nigricans, compared with 30% in the moderate exercise group and 40% in the inactive group.
Acanthosis nigricans (AN) shares similar "dirty" brown, confluent textural plaques, as well as nonspecific acanthosis and papillomatosis on histopathologic examination.
Obesity-related conditions included asthma, depression, dyslipidemia, sleep apnea, diabetes, hypertension, tibia vara, acanthosis nigricans, steatohepatitis, dysmetabolic syndrome, and hyperinsulinemia.
Histologically, the trademark of FEH is dramatic acanthosis of the oral epithelium.
Findings in early lesions may be nonspecific and may include mild acanthosis, papillary dermal oedema and lymphocyte-predominant dermal infiltrate.