acanthocytosis


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Related to acanthocytosis: retinitis pigmentosa, Neuroacanthocytosis, stomatocytosis

acanthocytosis

 [ah-kan″tho-si-to´sis]
the presence in the blood of acanthocytes.

a·can·tho·cy·to·sis

(ă-kan'thō-sī-tō'sis),
A rare condition in which the most of erythrocytes are acanthocytes; a regular feature of abetalipoproteinemia; also sometimes present in severe hepatocellular disease.

acanthocytosis

/acan·tho·cy·to·sis/ (ah-kan″tho-si-to´sis) the presence in the blood of acanthocytes, characteristic of abetalipoproteinemia and sometimes used synonymously.

acanthocytosis

[akan′thōsītō′sis]
Etymology: Gk, akantha + kytos + osis, condition
the presence of acanthocytes on a peripheral blood film, most commonly associated with abetalipoproteinemia, in which as many as 80% of the erythrocytes are acanthocytes. See also abetalipoproteinemia. Compare crenated erythrocytes. See also abetalipoproteinemia. Compare elliptocytosis.

acanthocytosis

(1) Abetalipoproteinemia, see there.
(2) A general term for the presence of acanthocytes in the peripheral blood.

Aetiology
Hereditary abetalipoproteinemia (hereditary acanthocytosis) accompanied by decreased total serum lipids, phospholipids, cholesterol, vitamin E, vitamin A; severe (end-stage) liver disease; hepatorenal failure; anorexia nervosa; chronic starvation. Small number of acanthocytes may be seen in severe haemolytic anaemia, especially post-splenectomy; haemolytic anaemia due to pyruvate kinase deficiency and intravascular mechanical defects (e.g., cardiac valve protheses, synthetic intravascular grafts and fibrin in DIC) in neonatal hepatitis after heparin administration; and rarely also in otherwise normal blood smears (one or 2 per smear), where they correspond to older, effete red cells approaching the end of their 120-day life-cycle.

acanthocytosis

1. Abetalipoproteinemia, see there.
2. A general term for the presence of acanthocytes in the peripheral blood. See Acanthocytes.

a·can·tho·cy·to·sis

(ă-kan'thō-sī-tō'sis)
A rare condition in which most erythrocytes are acanthocytes; a regular finding in abetalipoproteinemia.

acanthocytosis

A disorder of red blood cells (erythrocytes) in which the cell surfaces show multiple spine-like projections. This occurs in ABETALIPOPROTEINAEMIA, severe liver disease, vitamin E deficiency (see VITAMINS) and other conditions.

acanthocytosis

the presence in the blood of acanthocytes.