acanthocyte


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a·can·tho·cyte

(ă-kan'thō-sīt),
An erythrocyte characterized by multiple spiny cytoplasmic projections, as in acanthocytosis.
[acantho- + G. kytos, cell]

acanthocyte

/acan·tho·cyte/ (ah-kan´tho-sīt) a distorted erythrocyte with protoplasmic projections giving it a “thorny” appearance; seen in abetalipoproteinemia and other conditions.

acanthocyte

[əkan′thəsīt′]
Etymology: Gk, akantha + kytos, cell
an abnormal peripheral blood film erythrocyte with irregular spurlike projections. Predominate in abetalipoproteinemia; fewer occur in liver disease. Compare burr cell, elliptocyte. See also abetalipoproteinemia,acanthocytosis.
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Acanthocyte

Acanthocyte

A densely stained spheroidal red cell with multiple (usually 5–12), irregularly distributed, thorn-like spicules of variable size, often with drumstick ends.
Aetiology Hereditary abetalipoproteinemia* (hereditary acanthocytosis), severe (end stage) liver disease, hepatorenal failure, anorexia nervosa, chronic starvation. A small number of acanthocytes may be seen in severe haemolytic anaemia, especially post splenectomy, haemolytic anaemia due to pyruvate kinase deficiency, in neonatal hepatitis, after heparin administration, and rarely also in otherwise normal blood smears (one or two per smear), where they correspond to older, effete red cells approaching their “expiration” date of 120 days.
*Accompanied by decreased total serum lipids, phospholipids, cholesterol, vitamin E, vitamin A

acanthocyte

Acanthrocyte Hematology An RBC with a irregularly spaced, pointed spicules, of varying shape and number–Greek, ακαντηο, spike; acanthocytes are seen in abetalipoproteinemia–hereditary acanthocytosis, as well as in alcoholic cirrhosis with hemolytic anemia, hemolytic anemia due to pyruvate kinase deficiency, in neonatal hepatitis, after heparin administration or splenectomy. See Red blood cells.

a·can·tho·cyte

(ă-kan'thō-sīt)
An erythrocyte characterized by spiny cytoplasmic projections.
[acantho- + G. kytos, cell]

acanthocyte

an erythrocyte with protoplasmic projections giving it a thorny appearance; may be seen in dogs with liver disease and related disturbances of lipid metabolism and in dogs with hemangiosarcoma. Morphologically similar to spur cells, but biochemically distinct. See also spur-cell anemia.
References in periodicals archive ?
Acanthocytes typically comprise 50% to 100% of erythrocytes in ABL and may result from vitamin E deficiency or altered membrane lipid composition.
Acanthocytes are found more frequently in peripheral smears from patients with AD; in some individuals, this increase was noted a decade before the onset of dementia.
less than]5%-10%) target cells, acanthocytes, spherocytes, and Pappenheimer bodies.