Acanthamoeba

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Acanthamoeba

 [ah-kan″thah-me´bah]
a genus of free-living ameboid protozoa found usually in fresh water or moist soil. Certain species, such as A. castella´ni, A. poly´phaga, A. astronyx´is, and A. culbert´soni, may occur as opportunistic human pathogens, causing an acute fatal or chronic infection of the eye, brain, liver, kidney, lung, pancreas, and skin in patients with underlying disease or in immunocompromised patients.

Acanthamoeba

(ă-kan'thă-mē'bă),
A genus of free-living ameba (family Acanthamoebidae, order Amoebida) found in and characterized by the presence of acanthopodia. Human infection includes invasion of skin or colonization following injury, corneal invasion and colonization, and possibly lung or genitourinary tract colonization; a few cases of brain or central nervous system invasion have occurred, but not solely by the olfactory epithelium route of entry as with the more virulent infections caused by Naegleria fowleri. Species responsible are chiefly Acanthamoeba culbertsoni, but cases have been reported involving Acanthamoeba castellanii, Acanthamoeba polyphaga, and Acanthamoeba astronyxis. Most cases have been chronic rather than fulminating and rapidly fatal as with N. fowleri infection.
[G. akantha, thorn, spine, + Mod. L. amoeba, fr. G. amoibē, change]

Acanthamoeba

/Acan·tha·moe·ba/ (ah-kan″thah-me´bah) a genus of free-living ameboid protozoa (order Amoebida) found usually in fresh water or moist soil. Certain species, such as A. astronyxis, A. castellanii, A. culbertsoni, A. hatchetti, A. polyphaga, and A. rhisodes, may occur as human pathogens.

Acanthamoeba

[əkan′thəmē′bə]
a genus of free-living ameboid protozoa typically found in moist soil and water. The organisms may enter the body through a break in the skin or even though the nasal mucosa, olfactory nerve, and mucous membranes of the eye. It may cause severe infections, such as keratitis (eye infection that can lead to blindness especially with contact lens wearers), and systemic infections of the lung, genitourinary system, brain, and central nervous system. Disseminated cutaneous lesions caused by this organism are seen particularly in patients with AIDS. Although an infection may be fatal, cases are more commonly chronic and can persist for months.

Acanthamoeba

A genus of free-living pathogenic amoebae, which are ubiquitous in the environment, the cycle of which consists of 2 stages: a trophozoite (which is 14–40 µm in diameter) and a cyst (which has a double-layered wall with a diameter of 12–16 µm).

Sources
Tap water, dust, soil, sewage, air-conditioning units.
 
Diseases caused by:
Amoebic keratitis, acanthamoeba granulomatous encephalitis.

Acanthamoeba

A genus of free-living pathogenic amoebas Sources tap water, dust, soil, sewage, air conditioning units. See Acanthamebiasis. Cf Leptomyxid, Naegleria.

Acanthamoeba

small amebae, found in soil and water; they have been found in tissue cultures and in sporadic cases of pneumonia, general systemic infection and can produce meningoencephalitis after experimental administration. Possibly associated with granulomatous encephalitis in greyhounds. Includes A. castellani, A. culbertsoni.
References in periodicals archive ?
Worryingly it also may well be that the disinfecting solutions we rely upon are not as effective as we think particularly against some strains of Pseudomonas which Acanthamoebae feed upon.
A small number (3/25) of clones showed closest similarity to acanthamoebae belonging to the T4 clade, which includes strains considered to be human pathogens, including some A.
The acanthamoebae were collected by washing the plates with saline and a standard inoculum of 1 x [10.
Genotyping of pathogenic Acanthamoebae isolated from clinical samples in Greece report of a clinical isolate presenting T5 genotype.
Waddlia chondrophila was isolated from the brain and nervous tissue of an aborted bovine fetus in Germany (2), and Parachlamydia acanthamoebae and other unidentifi ed Chlamydia-like species were identified in 18.
Parachlamydia acanthamoebae and Protochlamydia naegleriophila belong to the family Parachlamydiaceae (1,4).
To the Editor: Parachlamydia acanthamoebae is a recently identified agent of pneumonia (1-3) and has been linked to adverse pregnancy outcomes, including human miscarriage and bovine abortion (4,5).
Parachlamydia acanthamoebae (2) is a Chlamydia-related organism considered as an emerging agent of pneumonia in humans.
but the specimens tested positive for acanthamoebae by PCR.
amoebophila (ATCC PRA-7), Simkania negevensis (ATCC VR-1471), Parachlamydia acanthamoebae strain Seine, Waddlia chondrophila (ATCC 1470), Neochlamydia hartmannellae (ATCC 50802), Criblamydia sequanensis (CRIB 18), and Rhabdochlamydia crassificans (CRIB 01) antigens were tested by micro-immunofluorescence against mouse anti-KNic antibodies, whereas KNic antigen was tested with serum against all these different Chlamydia-like organisms (9).
We investigated the role of Parachlamydia acanthamoebae in bovine abortion.
Genotyping of pathogenic acanthamoebae isolated from clinical samples in Greece: report of a clinical isolate presenting T5 genotype.