abuse liability


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abuse liability

The propensity of a drug to produce compulsive use, to cause addiction.
See also: liability
References in periodicals archive ?
The two university sponsored studies found an abuse liability of bupropion, and the two studies that were partly sponsored by pharmaceutical companies found no abuse liability.
Perhaps tolerance sets in to the unpleasant effects and perhaps drug abuse liability is higher under these conditions," he speculated.
today announced that it has initiated a Phase 1 clinical trial of EB-1020, a next-generation drug in development for treating adult attention deficit hyperactivity disorder (ADHD), with low risk of drug abuse liability.
Complete Category 3 oral human abuse liability study of Egalet-002;
The abuse-deterrent characteristics of Egalet-001 have been demonstrated in Category 1 abuse-deterrent studies and a recently announced Category 3 oral human abuse liability (HAL) study which showed that the abuse potential of manipulated Egalet-001 taken orally was significantly lower than that for manipulated MS Contin (morphine sulfate controlled-release).
today announced that it has presented preclinical data demonstrating that EB-1020, a next-generation product candidate for adult attention deficit/hyperactivity disorder (ADHD), may be effective for treating ADHD without the burden of drug abuse liability.
Strain's research focuses on substance abuse treatment, the abuse liability of novel medications, and the development of new pharmacotherapies for substance abuse treatment (including opioids and alcohol), among other areas.
The company integrates CRI's leadership in psychiatry and expertise in complex studies with Lifetree's widely recognized clinical trial management and site expertise in Phase I-III pain management and abuse liability studies.
The MorphaBond ER development program encompassed multiple in vitro, pharmacokinetic, and human abuse liability, or drug "liking", studies.
There is no evidence that OXECTA has a reduced abuse liability compared to immediate-release oxycodone.
Research suggests this profile could be optimal for the treatment of adult ADHD while avoiding the drug abuse liability of stimulants.