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abruptio placentae

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ab·rup·ti·o pla·cen·tae (-brpsh- pl-snt)
n.
The premature detachment of a normally situated placenta.

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Research into the mechanisms responsible for abruptio placentae suggest that folate deficiency and defects within the methionine-homocysteine metabolic pathway increase the risk of placental vascular disease, including abruptio placentae (11).
Although there is no direct proof of a cause-and-effect relation, the evidence suggests that a deficiency is associated with abruptio placentae, spontaneous abortion, preeclampsia, fetal malformations, and subnormal infant development.
 
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