abdominoperineal resection


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abdominoperineal resection (APR),

a surgical cancer treatment involving resection of the lower sigmoid colon, rectum, anus, and surrounding skin and formation of a sigmoid colostomy; performed as a synchronous or sequential transabdominal and perineal procedure.

abdominoperineal resection

The surgical excision of the lower rectum and anus, resulting in the loss of the anal sphincter and a need for colostomy.

Results
Local control, 60–80%; 60–90% 5-year survival; for larger lesions, RT and 5-FU and mitomycin are used. 

APR is less preferred than RT for small lesions + external beam treatment or with radioactive implants—e.g., 198Iridium seeds.

ab·dom·i·no·per·i·ne·al re·sec·tion

(ab-dom'i-nō-per-i-nē'ăl rē-sek'shŭn)
A surgical treatment for cancer involving resection of the lower sigmoid colon, rectum, anus, and surrounding skin, and formation of a sigmoid colostomy; performed as a synchronous or sequential transabdominal and perineal procedure.
References in periodicals archive ?
The patient was informed about the radical cystoprostatectomy and abdominoperineal resection if organ preservation was unfavourable, and informed consent was obtained.
Before the 1970s - 1980s this disease was treated surgically with abdominoperineal resection (APR) resulting in a permanent colostomy.
The patient proceeded to surgery and underwent an abdominoperineal resection with stoma formation, recovery was uneventful.
A 72-year-old man undergoing an abdominoperineal resection of the rectum had a 14 G central venous catheter (CVC) inserted preoperatively via the jugular route.
Historically, surgery for carcinoma of the rectum included abdominoperineal resection and permanent colostomy.
Subsequently the patient was offered and received a laparoscopic abdominoperineal resection.
The diagnosis of spindle cell melanoma was made, and abdominoperineal resection with vaginal excision was performed.
Because the distal surgical margin was invaded with tumor, he was reoperated and an abdominoperineal resection was performed.
More specific applications include: stoma reversal, paraesophageal/hiatal hernia repair, breast reconstruction using pedicled TRAM flap, abdominoperineal resection and abdominal wall reconstruction.
Recent trends favor local excision when technically feasible, although some patients may require an abdominoperineal resection of the rectum, especially for larger tumors.
The patient subsequently underwent abdominoperineal resection without complications.