Global Clinical Trials Review, H2, 2015 provides an overview of worldwide abdominal abscess
clinical trials scenario and provides top line data, information by region, country, phase and more.
The necrotic tissue of the wall weakened and allowed bacteria to seed the peritoneal cavity, resulting in inflammation of the peritoneum, formation of abdominal abscess
, and sepsis.
He died last February from an abdominal abscess
but the inquest heard that, despite specific instructions by his consultant that food was not to be administered via a feeding tube, a student dietician arranged for this to happen.
To better identify which patients are most likely to have serious infections, they further investigated characteristics of the 22 patients who were found to have pneumonia (10), bacteremia (6), wound infection (3), sepsis (2), fistula (2), abdominal abscess
(1), or Clostridium difficile (1).
A uterine cancer and an abdominal abscess
were suspected, and the gynecologist wanted to operate as soon as possible.
The adverse reactions reported during clinical trials were blood fibrinogen increased, post procedural and intra-abdominal hemorrhage, abdominal distension, anemia, gastrointestinal hemorrhage, thoracic cavity drainage, pleural effusion, post-procedural bile leak, abdominal abscess
, ascites, deep vein thrombosis, localized intra-abdominal fluid collection, and pulmonary embolism.
An abdominal CT scan with IV contrast was performed demonstrating an oedematous pancreas and reduced enhancement, consistent with acute pancreatitis with associated inflammatory changes in the surrounding soft tissues but no evidence of intra abdominal abscess
, collection or pseudocyst.
Serious infections including pyelonephritis, septic arthritis, abdominal abscess
, osteomyelitis, pneumonia and sepsis have been reported in the clinical trials in patients on etanercept.
A favorable response was seen in 9 of 9 patients with peritonitis, 3 of 4 with abscesses (liver, parasplenic, and urinary bladder abscesses), 2 of 2 with pleural space infections, 1 of 2 with mixed peritoneal and pleural infection, 1 of 1 with mixed abdominal abscess
and peritonitis, and 0 of 1 with Candida pneumonia.
Bard's mesh patch caused serious medical complications for many patients including bowel perforation, sepsis, intestinal fistulas, and abdominal abscess
The strain was isolated from vaginal swab specimens from a 68-year-old woman with smoldering myeloma and chronic hepatitis C virus infection who was hospitalized for abdominal abscess
This point is especially important in the management of infected pseudocysts, because the existing infection must be prevented from spreading to peripheral tissues and causing an abdominal abscess