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abarelix

   Also found in: Wikipedia 0.02 sec.
abarelix,
a gonadotropin-releasing hormone antagonist.
indication This drug is used in palliative treatment of prostate cancer.
contraindications Pregnancy, latex allergy, lactation, and known hypersensitivity to this drug prohibit its use. It is also contraindicated for use in children.
adverse effects Adverse effects of this drug include breast enlargement, nipple tenderness, pain on injection, local site reactions, and decreased bone density (with long-term treatment). Life-threatening side effects include anaphylaxis and systemic allergic reaction. Common side effects include headache, dizziness, fatigue, sleep disturbance, nausea, constipation, diarrhea, dysuria, urinary frequency, urinary retention, urinary tract infection, pain (including back pain), and hot flashes.


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The market for hormone-suppressing drugs such as Abarelix is believed to be $2 billion annually, said Amgen spokesman David Kaye.
Abarelix was approved in November 2003 for the palliative treatment of men with advanced symptomatic prostate cancer.
Amgen also is scheduled to present the results of phase three studies of a prostate cancer drug, Abarelix, which it developed along with Praecis Pharmaceuticals.
 
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