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abacavir

   Also found in: Acronyms, Wikipedia 0.03 sec.
abacavir /abac·a·vir/ (ah-bak´ah-vir) a nonnucleoside reverse transcriptase inhibitor used as the sulfate salt as an antiretroviral in the treatment of human immunodeficiency virus infection.
abacavir,
an antiviral that is a nucleoside reverse transcriptase inhibitor.
indication It is prescribed in combination with other antiretroviral agents for HIV-1 infection.
contraindication Known hypersensitivity to this drug prohibits its use.
adverse effects Hypersensitivity reactions occur in approximately 5% of patients, and can be fatal. Other life-threatening adverse effects include granulocytopenia, anemia, and lactic acidosis. Common side effects include fever, headache, malaise, insomnia, nausea, vomiting, diarrhea, anorexia, and rash.

abacavir
Ziagen, zintavir, 1592 AIDS An HIV nucleoside reverse transcriptase inhibitor–NRTI/integrase inhibitor similar to AZT Adverse effects Life-threatening allergic reactions–fever, dyspnea, rashes, intraoral blistering, nausea, headache. See AIDS, Nucleoside reverse transcriptase inhibitor, Reverse transcriptase.


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A study in Australia showed that a genetic test was very effective in predicting which patient would react badly to abacavir (Ziagen) [1,2].
Each day, half the volunteers received one pill containing efavirenz and another containing abacavir and lamivudine.
[double dagger] Combivir[R] tablets contain 150 mg lamivudine / 300 mg zidovudine, Trizivir[R] tablets contain 300 mg abacavir, 150 mg lamivudine, 300 mg zidovudine.
 
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