alpha1-antitrypsin deficiency panniculitis

(redirected from a1-antitrypsin deficiency panniculitis)

α1-an·ti·tryp·sin de·fi·cien·cy pan·nic·u·li·tis

multiple painful subcutaneous nodules occurring in patients with severe antitrypsin deficiency; biopsies show lobular panniculitis with neutrophils and foamy histiocytes. Some patients formerly diagnosed with Weber-Christian disease show this deficiency.