plasminogen activator
[plaz-min´o-jen ak´tĭ-va″tor] any of a group of substances that cleave plasminogen and convert it to plasmin, its active form, e.g., tissue plasminogen activator.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
plas·min·o·gen ac·ti·va·tor
a proteinase converting plasminogen to plasmin by cleavage of an Arg-Val bond in the former.
Farlex Partner Medical Dictionary © Farlex 2012
plas·min·o·gen ac·ti·va·tor
(plaz-min'ŏ-jen ak'ti-vā-tŏr) A proteinase that converts plasminogen to plasmin by cleavage of a single (usually Arg-Val) bond in the former. Prevents formation of fibrin clots. Alteplase and streptokinase are examples of medications that promote thrombolysis by activating plasminogen.
Synonym(s):
urokinase.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
plas·min·o·gen ac·ti·va·tor
(plaz-min'ŏ-jen ak'ti-vā-tŏr) A proteinase that converts plasminogen to plasmin and prevents formation of fibron clots.
Synonym(s):
urokinase.
Medical Dictionary for the Dental Professions © Farlex 2012