nelfinavir
[nel-fin´ah-vir] an
HIV protease inhibitor used as the mesylate salt in treatment of human immuno deficiency virus infection and
acquired immunodeficiency syndrome; administered orally.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
nelfinavir
(nĕl-fĭn′ə-vîr)n. A protease-inhibiting drug given in the form of its mesylate, often with other drugs, to suppress the replication of HIV.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
nelfinavir
A potent HIV protease inhibitor, which is combined with reverse transcriptase inhibitors—e.g., Retrovir (AZT), zidovudine and Epivir (3TC, lamivudine)—acting at late stages in the HIV life cycle.
Side effects
Diarrhoea, 20%, increased liver function tests (LFTs), lipodystrophy.
Contraindicated drugs
Nelfinavir inhibits the cytochrome P-450 system, precluding co-administration of agents (e.g., amiodarone, astemizole, cisapride, ergot derivatives, midazolam, quinidine, rifampin, terfenadine, triazolam) which are metabolised by the P-450 system.Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
nelfinavir
Viracept® AIDS A potent HIV protease inhibitor, used with reverse transcriptase inhibitors–eg, Retrovir–AZT, zidovudine and Epivir–3TC, lamivudine; it acts at late stages in the viral life cycle Side effects Diarrhea–20%, ↑ LFTs, lipodystrophy. See AIDS, Antiretroviral, HIV, Protease inhibitors. Cf Reverse transcriptase inhibitor. McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
nelfinavir
A protease inhibitor drug used in combination with other antiretroviral drugs to treat HIV infections. The drug is on the WHO official list. A brand name is Viracept.Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005