inclusion body myositis

inclusion body myositis

a slowly progressive inflammatory myopathy with a male predominance and preferential weakness onset in the quadriceps muscles, finger flexors, or pharyngeal muscles. Inflammatory infiltrate can be observed, with a predominance of CD8⁺ T cells.

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inclusion body myositis

A type of idiopathic myositis that is not autoimmune and does not respond to immunosuppressive therapy, a clinical diagnosis of exclusion, confirmed by typical histologic features Clinical Slowly progressive disease of middle-aged ♂, beginning in legs, causing atrophy and weakness of quadriceps, sparing facial and oropharyngeal muscles EMG Abnormal electrical 'irritation', slowing of nerve conduction and ↑ wave amplitude

McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.